Results 1 to 10 of about 186,106 (305)

Baseline Lenacapavir Resistance and Capsid Variability in Bulgaria: A Next-Generation Sequencing Study of Newly Diagnosed HIV-1 Infections [PDF]

Pathogens
Lenacapavir, the first approved HIV-1 capsid inhibitor, is now being introduced for both treatment and pre-exposure prophylaxis, yet the capsid-coding region lies outside the pol fragment examined in routine genotypic resistance testing, and baseline ...
Ivailo Alexiev, Aleksandra Partsuneva, Reneta Dimitrova, Asya Kostadinova, Anna Gancheva, Lyubomira Grigorova, Kristina Stoyanova, Maria Nikolova, Radoslava Emilova, Nina Yancheva, Dimitar Strashimirov, Ivan Baltadzhiev, Tsetsa Doychinova, Pavlina Parusheva, Ivelina Todorova   +14 more
doaj   +2 more sources

DISTINCTIVE SIRE1 RETROTRANSPOSON PATTERNS ON BARLEY CHROMOSOMES?

Trakya University Journal of Natural Sciences, 2021
SIRE1 is an active and relatively high copy-number retroelement belongs to the Tyl/Copia long terminal repeat (LTR) retrotransposon superfamily. Distinctive SIRE1 elements (ENV and GAG) distributions in barley genome were observed by using fluorescent in
Nermin Gozukirmizi, Elif Karlık
doaj   +1 more source

Mutation in the Disordered Linker Region of Capsid Disrupts Viral Kinetics of a Neuropathogenic SIV in Rhesus Macaques

Microbiology Spectrum, 2022
TRIM5α polymorphism in rhesus macaques (RM) limits the genetic pool of animals in which we can perform simian immunodeficiency virus (SIV) studies without first screening animals for permissive TRIM5α genotypes.
Cheri A. Lee, Vanessa M. Hirsch
doaj   +1 more source

Analysing the HERV-K env, np9, rec and gag expression in cervical tissues

New Microbes and New Infections, 2021
Cervical cancer is considered to be the fourth common cancer. It is assumed that numerous risk factors, especially infectious ones, can have a detrimental effect on cervical cancer.
S. Tavakolian, H. Goudarzi, A. Moridi, E. Faghihloo   +3 more
doaj   +1 more source

Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity

Viruses, 2021
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl, Mehmet H. Guney, Teresa Vanzo, Pyae P. Kyawe, Judith M. White, Massimo Pizzato, Jeremy Luban   +6 more
doaj   +1 more source

Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques

Frontiers in Immunology, 2022
Immunogenicity of HIV-1 mRNA vaccine regimens was analyzed in a non-human primate animal model. Rhesus macaques immunized with mRNA in lipid nanoparticle (mRNA/LNP) formulation expressing HIV-1 Gag and Gag conserved regions (CE) as immunogens developed ...
Antonio Valentin, Cristina Bergamaschi, Margherita Rosati, Matthew Angel, Matthew Angel, Robert Burns, Mahesh Agarwal, Janina Gergen, Benjamin Petsch, Lidia Oostvogels, Edde Loeliger, Kara W. Chew, Steven G. Deeks, James I. Mullins, James I. Mullins, James I. Mullins, George N. Pavlakis, Barbara K. Felber   +17 more
doaj   +1 more source

Glycosaminoglycan-Inspired Biomaterials for the Development of Bioactive Hydrogel Networks

Molecules, 2020
Glycosaminoglycans (GAG) are long, linear polysaccharides that display a wide range of relevant biological roles. Particularly, in the extracellular matrix (ECM) GAG specifically interact with other biological molecules, such as growth factors ...
Mariana I. Neves, Marco Araújo, Lorenzo Moroni, Ricardo M.P. da Silva, Cristina C. Barrias   +4 more
doaj   +1 more source

Homenaje a Chaplin y al cine burlesco en la trilogía novelesca de Jardiel Poncela

Cuadernos de Investigación Filológica, 2017
Este artículo analiza la influencia del cine burlesco de los años 20 en la trilogía novelesca de Enrique Jardiel Poncela en la que se multiplican las referencias y alusiones a Charles “Charlie” Chaplin y al personaje mítico creado por él. En esta obra se
Cécile François
doaj   +1 more source

Dorsal Fusion as Correction of Craniocervical and Atlantoaxial Instability in Patients with Benign and Malignant Lesions using O-Arm System

Global Spine Journal, 2016
Introduction A retrospective and prospective analysis of the surgical treatment and results of 99 patients with benign and malignant craniocervical, atlantoaxial and high cervical lesions operated during 36 – month period (2011–2014) at the Department of
Nikolay Mirchev, Robert Behr
doaj   +1 more source

Awareness and prevention of patient gag reflex among pedodontists in India: A web-based survey

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2016
Aim: The aim of this study is to devise a reliable and valid web-based survey to predict the awareness level and prevention of patient's gag reflex among Indian pedodontists.
Soumik Roy, Deepak P Bhayya, Shilpi Gupta, Kanchi Upadhyay, Sonia Tiwari, Ashish Rao   +5 more
doaj   +1 more source