Results 31 to 40 of about 186,106 (305)
Protease mediated maturation of HIV: Inhibitors of protease and the maturation process [PDF]
, 2012 Protease-mediated maturation of HIV-1 virus particles is essential for virus infectivity. Maturation occurs concomitant with immature virus particle release and is mediated by the viral protease (PR), which sequentially cleaves the Gag and Gag-Pol ...
Catherine S. Adamson +2 more
core +1 more source
HIV Research & Clinical Practice, 2019 To understand the pathogenesis of low level viraemia (LLV) in HIV-infected patients on boosted protease inhibitors (PI/b), we enrolled 34 subjects with a median HIV-RNA 79 copies/mL and followed them for 15 months.
Francesca Ferretti +7 more
doaj +1 more source
, 2008 The egress of HIV particles from virus-infected cells is accomplished by the recruitment of proteins that normally mediate host cell endocytic functions.
Gam, Jongsik +5 more
core +1 more source
Quantitative Live-Cell Imaging of Human Immunodeficiency Virus (HIV-1) Assembly [PDF]
, 2012 Advances in fluorescence methodologies make it possible to investigate biological systems in unprecedented detail. Over the last few years, quantitative live-cell imaging has increasingly been used to study the dynamic interactions of viruses with cells ...
Barbara Müller +5 more
core +1 more source
Gag-ABCE1 colocalization in situ upon provirus expression.
, 2018 (A) PLA was used to detect regions in which Gag is within 40 nm from ABCE1 in situ, with concurrent αGag IF for quantification of intracellular Gag levels. An experimental schematic for PLA methods is shown.
Brook C. Barajas (5109236) +6 more
core +1 more source
Gag-H protein expression with anti-Gag-H clone 14H11G1.
, 2016 Overlay of histograms obtained by flow cytometric analyses of 11 CRC cell lines with no primary antibody (filled light grey surface), irrelevant antibody (anti-His; 2G2B3; grey line) and anti-Gag-H antibody (clone 14H11G1; black line) are presented in ...
Michael Linnebacher (180341) +9 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
HIV Pol inhibits HIV budding and mediates the severe budding defect of Gag-Pol. [PDF]
PLoS ONE, 2012 The prevailing hypothesis of HIV budding posits that the viral Gag protein drives budding, and that the Gag p6 peptide plays an essential role by recruiting host-cell budding factors to sites of HIV assembly. HIV also expresses a second Gag protein, p160
Xin Gan, Stephen J Gould
doaj +1 more source
Gag-DDX6 colocalization in situ upon provirus expression.
, 2018 (A) PLA was used to detect regions in which Gag is within 40 nm from DDX6 in situ, with concurrent αGag IF for quantification of intracellular Gag levels. An experimental schematic for PLA methods is shown.
Brook C. Barajas (5109236) +6 more
core +1 more source