Results 1 to 10 of about 82,235 (307)
Incorporation of chimeric HIV-SIV-Env and modified HIV-Env proteins into HIV pseudovirions
Virology, 2007 Low level incorporation of the viral glycoprotein (Env) into human immunodeficiency virus (HIV) particles is a major drawback for vaccine strategies against HIV/AIDS in which HIV particles are used as immunogen. Within this study, we have examined two strategies aimed at achieving higher levels of Env incorporation into non-infectious pseudovirions ...
Tanya Pfeiffer, Valerie Bosch
exaly +4 more sources
Immunogenicity of HIV-1 Env mRNA and Env-Gag VLP mRNA Vaccines in Mice
VaccinesBackground: The development of a protective vaccine is critical for conclusively ending the human immunodeficiency virus (HIV) epidemic. Methods: We constructed nucleotide-modified mRNA vaccines expressing HIV-1 Env and Gag proteins.
Qi Ma +5 more
doaj +4 more sources
Env Exceptionalism: Why Are HIV-1 Env Glycoproteins Atypical Immunogens? [PDF]
Cell Host and Microbe, 2020 Recombinant HIV-1 envelope (Env) glycoproteins of ever-increasing sophistication have been evaluated as vaccine candidates for over 30 years. Structurally defined mimics of native trimeric Env glycoproteins (e.g., SOSIP trimers) present multiple epitopes for broadly neutralizing antibodies (bNAbs) and their germline precursors, but elicitation of bNAbs
Per Johan Klasse +2 more
exaly +5 more sources
A novel, machine learning-based feature extraction method for detecting and localizing bearing component defects [PDF]
Metrology and Measurement Systems, 2022 Vibration analysis for conditional preventive maintenance is an essential tool for the industry. The vibration signals sensored, collected and analyzed can provide information about the state of an induction motor.
Bilal Djamal Eddine Cherif +2 more
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SPATIOTEMPORAL FUSION OF HIGH RESOLUTION LAND SURFACE TEMPERATURE USING THERMAL SHARPENED IMAGES FROM REGRESSION-BASED URBAN INDICES [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2020 Obtaining spatially continuous, high resolution thermal images is crucial in order to effectively analyze heat-related phenomena in urban areas and the inherent high spatial and temporal variations.
M. Kim, K. Cho, H. Kim, Y. Kim
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مجله دانشکده پزشکی اصفهان, 2021 Background: Breast cancer is one of the most common malignancies in women worldwide. Global Cancer Observatory (GLOBOCAN) data for 2019 show that about two million women are diagnosed with breast cancer each year. Human endogenous retroviruses (HERV) can
Mahdiyeh Miralimalek +4 more
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DISTINCTIVE SIRE1 RETROTRANSPOSON PATTERNS ON BARLEY CHROMOSOMES?
Trakya University Journal of Natural Sciences, 2021 SIRE1 is an active and relatively high copy-number retroelement belongs to the Tyl/Copia long terminal repeat (LTR) retrotransposon superfamily. Distinctive SIRE1 elements (ENV and GAG) distributions in barley genome were observed by using fluorescent in
Nermin Gozukirmizi, Elif Karlık
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Virulence, 2021 Avian leukosis virus subgroup J (ALV-J) generally induces hemangioma, myeloid leukosis, and immunosuppression in chickens, causing significant poultry industry economic losses worldwide. The unusual env gene of ALV-J, with low homology to other subgroups
Tuofan Li +10 more
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Specific Substitutions in Region V2 of gp120 env confer SHIV Neutralisation Resistance
Pathogens, 2020 A tier 2 SHIV-MK38 strain was obtained after two in vivo passages of tier 1 SHIV-MK1. SHIV-MK38#818, cloned from the MK38 strain, was neutralisation-resistant, like the parental MK38 strain, to SHIV-infected monkey plasma (MP), HIV-1-infected human ...
Yalcin Pisil +4 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 West Nile virus (WNV) is a mosquito-borne virus of public health importance. Currently, there is no FDA approved vaccine available against WNV infection in humans. Therefore, the early diagnosis of the WNV infection is important for epidemiologic control
Priyanka Singh Tomar +3 more
doaj +1 more source