HIV Env conserved element DNA vaccine alters immunodominance in macaques
Sequence diversity and immunodominance are major obstacles in the design of an effective vaccine against HIV. HIV Env is a highly-glycosylated protein composed of ‘conserved’ and ‘variable’ regions.
Xintao Hu +12 more
doaj +1 more source
Estimating eDNA shedding and decay rates for muskellunge in early stages of development
Estimating population size and species distribution is essential for fisheries management and conservation. Traditionally, estimates rely on live‐capture and visual surveys; however, these approaches are challenging for low density or elusive species and
Maxwell L. Wilder +2 more
doaj +1 more source
Green Hospitals for the Future of Healthcare: A Review
Hospitals are essential for preserving and enhancing both human and environmental health. The "green hospital" concept seeks to redefine how medical facilities are constructed to preserve human life while protecting the environment.
Athra Alkaabi, Mohammad Aljaradin
doaj +1 more source
Local generalised method of moments: an application to point process-based rainfall models [PDF]
Long series of simulated rainfall are required at point locations for a range of applications, including hydrological studies. Clustered point process-based rainfall models have been used for generating such simulations for many decades.
Austin +37 more
core +1 more source
Establishment of an avian leukosis virus subgroup A-resistant cell line
Rapid diagnostic methods for classifying avian leukosis subgroups in the field were needed for routine, large-scale screening. As a first step in method development, we inserted the avian leukosis virus subgroup A (ALV-A) env gene into plasmid pcDNA3.1 ...
Min FENG +3 more
doaj +1 more source
Genetic diversity in the env V1-V2 region of proviral quasispecies from long-term controller MHC-typed cynomolgus macaques infected with SHIVSF162P4cy [PDF]
Intra-host evolution of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) has been shown by viral RNA analysis in subjects who naturally suppress plasma viremia to low levels, known as controllers.
Borsetti, Alessandra +11 more
core +1 more source
Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. [PDF]
Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells.
Amara, Rama R +21 more
core
Endogenous retroviruses (ERVs) are retroviral sequences that remain fixed in the host genome, where they could play an important role. Some ERVs have been identified in insects and proven to have infectious properties.
Min Feng +5 more
doaj +1 more source
An N-terminally truncated envelope protein encoded by a human endogenous retrovirus W locus on chromosome Xq22.3 [PDF]
Background We previously showed that the envelope (env) sequence of a human endogenous retrovirus (HERV)-W locus on chromosome Xq22.3 is transcribed in human peripheral blood mononuclear cells.
Christina Roebke +7 more
core +3 more sources
Complete genome sequences of two feline Leukemia virus subgroup B isolates with novel recombination sites [PDF]
It is generally accepted that all primary isolates of feline leukemia virus (FeLV) contain a subgroup A virus (FeLV-A) that is essential for transmission.
Bae +12 more
core +1 more source

