Results 1 to 10 of about 12,723,792 (140)
Regulation of human immunodeficiency virus env expression by the rev gene product [PDF]
Journal of Virology, 1989 A single simian virus 40 late replacement vector which expresses both the rev and envelope (env) genes of human immunodeficiency virus was used to examine the mechanism underlying the dependence of env gene expression on the rev protein. When rev was deleted from the vector, no envelope protein expression could be detected in transfected cells, and the
M L, Hammarskjöld +5 more
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Mutational analysis of the human immunodeficiency virus type 1 env gene product proteolytic cleavage site [PDF]
Journal of Virology, 1990 The structural requirements for proteolytic cleavage of the human immunodeficiency virus type 1 env gene product, gp160, to gp120 and gp41 have been assessed by specific mutagenesis of the sequence Lys Ala Lys Arg Arg Val Val Glu Arg Glu Lys Arg located between amino acids 500 and 511, i.e., at the putative C terminus of gp120.
V, Bosch, M, Pawlita
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Human endogenous retrovirus-K(II) envelope induction protects neurons during HIV/AIDS. [PDF]
PLoS ONE, 2014 Human endogenous retroviruses (HERVs) are differentially expressed depending on the cell type and physiological circumstances. HERV-K has been implicated in the pathogenesis of several diseases although the functional consequences of its expression ...
Rakesh K Bhat +7 more
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A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products. [PDF]
PLoS Pathogens, 2018 The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus ...
Young C Shin +8 more
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Dynamic Post-Transcriptional Regulation of HIV-1 Gene Expression
Biology, 2012 Gene expression of the human immunodeficiency virus type 1 (HIV-1) is a highly regulated process. Basal transcription of the integrated provirus generates early transcripts that encode for the viral products Tat and Rev.
Alessandro Marcello, Anna Kula
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Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.
PLoS Pathogens, 2019 A prophylactic vaccine against human immunodeficiency virus (HIV) remains a top priority in biomedical research. Given the failure of conventional immunization protocols to confer robust protection against HIV, new and unconventional approaches may be ...
Lucas Gonzalez-Nieto +16 more
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Virology, 2000 The occurrence of human immunodeficiency virus type 1 (HIV-1) recombinant genomes belonging to different subtypes is a common event in regions where more than two subtypes cocirculate. Although there are accumulating data toward an increase in the number of intersubtype recombinants, little has been addressed about the biological behavior of such ...
Costa, Luciana Jesus da UNIFESP +3 more
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Virology JournalBackground The human immunodeficiency virus type 1 (HIV-1) pandemic continues to pose a significant global public health challenge. Recombination between HIV-1 variants generates unique recombinant forms (URFs) and then circulating recombinant forms ...
Xuemei Ling +11 more
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Molecular Epidemiology and Phylogenetic Analysis of HTLV-1 in HIV-1-infected Patients in Tehran, Iran. [PDF]
J Med VirolAbyar S +5 more
europepmc +1 more source