Results 21 to 30 of about 12,723,792 (140)

Mapping the domains of CD134 as a functional receptor for feline immunodeficiency virus (FIV) [PDF]

, 2006
The feline homologue of CD134 (fCD134) is the primary binding receptor for feline immunodeficiency virus (FIV), targeting the virus preferentially to activated CD4+ helper T cells.
Bonci, F., Hosie, MJ, Bonci F, Willett BJ, Hosie MJ, Bonci, F, McMonagle, E.L., Hosie, M.J., Pistello, M, McMonagle EL, McMonagle, EL, Willett, B.J., Willett, BJ, PISTELLO, MAURO, Pistello, M.   +14 more
core   +1 more source

Simian immunodeficiency virus (SIV) molecular epidemiology in non-human primates from West Africa [PDF]

, 2008
It is now scientifically proved that the human immunodeficiency viruses, HIV-1 and HIV-2, are the results of cross-species transmissions of the simian immunodeficiency viruses (SIV) that naturally infect non-human primates in sub- Saharan Africa ...
Locatelli, Sabrina
core   +1 more source

Induction of cytolytic T lymphocytes directed towards the V3 loop of the human immunodeficiency virus type 1 external glycoprotein gp120 by p55gag/V3 chimeric vaccinia viruses [PDF]

, 1993
T cell-mediated cytotoxicity may play an important role in controlling infection by human immunodeficiency virus (HIV). In order to study the ability of rationally designed antigens to induce cytolytic T lymphocytes (CTLs) we replaced stretches of 30 to ...
Deml, Ludwig, Böltz, T., Wagner, Ralf, Modrow, Susanne, Wolf, Hans J.   +4 more
core   +1 more source

The role of the chemokine receptor CXCR4 in infection with feline immunodeficiency virus [PDF]

, 1999
Infection with feline immunodeficiency virus (FIV) leads to the development of a disease state similar to AIDS in man. Recent studies have identified the chemokine receptor CXCR4 as the major receptor for cell culture-adapted strains of FIV, suggesting ...
Hosie, M.J., Willett, B.J., Margaret J. Hosie, Brian J. Willett,   +3 more
core   +1 more source

Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence [PDF]

, 2002
The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic.
Hosie, M.J., Dunsford, T.H., Shimojima, M., Klein, D., Willett, B.J., Neil, J.C., Jarrett, O., Cannon, C.   +7 more
core   +1 more source

Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]

, 2011
Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Bridge, S., Skinner, Michael A., Anson, Donald, Dennis, M., Simon H Bridge, Dowall, S., Blanchard, Tom J., Getty, B., Stewart, James, Dennis, Mike J., Dowall, SD, Donald S Anson, Anson, D., Dennis, MJ, Bridge, Simon H., Dowall, Stuart D., Blanchard, Thomas, Stewart, JP, Blanchard, T., Skinner, M., Stewart, James P., James P Stewart, Mike J Dennis, Getty, B, Michael A Skinner, Bridge, SH, Bridge, Simon, Sharpe, Sally, Sharpe, SA, Skinner, MA, Getty, Brian, Brian Getty, Dennis, Mike, Blanchard, Tom, Sharpe, Sally A., Anson, DS, Sally A Sharpe, Skinner, Michael, Stuart D Dowall, Tom J Blanchard, Blanchard, TJ, Anson, Donald S., Stewart, J., Sharpe, S., Dowall, Stuart   +44 more
core   +1 more source

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection [PDF]

, 2009
Background: There is currently no effective AIDS vaccine, emphasizing the importance of developing alternative therapies. Recently, a patient was successfully transplanted with allogeneic, naturally resistant CCR5-negative (CCR5 delta 32) cells, setting ...
Trobridge, Grant D., Chiu Sum Ying, Brian C Beard, Robert A Wu, John J Rossi, Muñoz Nina M., Nina M Muñoz, John J. Rossi, Brian C. Beard, Dorothee von Laer, Laer, Dorothee von, Grant D Trobridge, Beard Brian C., Chiu, Sum Ying, Nina M. Muñoz, Kiem, Hans-Peter, Sum Ying Chiu, Trobridge Grant D., Wu, Robert A., Hans-Peter Kiem, Kiem Hans-Peter, Beard, Brian C., Wu Robert A., von Laer Dorothee, Rossi, John J., Rossi John J., Grant D. Trobridge, Robert A. Wu, Muñoz, Nina M.   +28 more
core   +2 more sources

The Impact of Domestic Public Health Spending on Health Outcomes in Sub‐Saharan Africa: Evidence From Disability‐Adjusted Life Years

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Sub‐Saharan Africa (SSA) continues to experience a high and uneven disease burden, mainly from HIV/AIDS, tuberculosis, and malaria. As external funding declines, the strategic allocation of domestic public health spending (DPHS) becomes crucial.
Wa Ntita Serge Kabongo, Josue Mbonigaba
wiley   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

N-terminally myristoylated feline foamy virus Gag allows Env-independent budding of sub-viral particles [PDF]

, 2011
Foamy viruses (FVs) are distinct retroviruses classified as Spumaretrovirinae in contrast to the other retroviruses, the Orthoretrovirinae. As a unique feature of FVs, Gag is not sufficient for sub-viral particle (SVP) release. In primate and feline FVs (
Löchelt, Martin, Martin Löchelt, Yong-Boum Kim, Liu, Yang, Yang Liu, Kim, Yong-Boum   +5 more
core   +1 more source