Results 11 to 20 of about 12,723,792 (140)

Molecular Evidence of Human T‑Cell Leukemia Virus Type 1 Transmission by Needlestick Injury in Healthcare Workers. [PDF]

J Med Virol
ABSTRACT Human T‑cell leukemia virus type 1 (HTLV‑1) is a retrovirus that spreads primarily through cell‐to‐cell transmission. Occupational transmission of HTLV‐1 by needlestick injury is considered exceedingly rare, with no reported molecularly confirmed cases.
Tokunaga M, Kuramitsu M, Saito M, Yoshimori M, Odawara J, Ito Y, Nakamura H, Sagara Y, Ishii M, Nojiri N, Yoshida-Furihata H, Kuribayashi W, Mizukami T, Miura K, Utsunomiya A.   +14 more
europepmc   +2 more sources

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]

, 2010
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
HAGIWARA, M. K., Richtzenhain, L.J., CRUZ, J. C. M., HOSIE, M. J., REIS, J. K. P., Hagiwara, M.K., Cruz, J.C.M., WILLETT, B. J., Hosie, M.J., Logan, N., Willett, B.J., BRANDAO, P. E., Teixeira, Bruno Marques, Reis, J.K.P., Brandão, P.E., RICHTZENHAIN, L. J.   +15 more
core   +1 more source

Assessment of HIV-1 entry inhibitors by MLV/HIV-1 pseudotyped vectors [PDF]

, 2005
Background: Murine leukemia virus (MLV) vector particles can be pseudotyped with a truncated variant of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) and selectively target gene transfer to human cells expressing both CD4 and an ...
Sandra Siegert, Barbara S Schnierle, Schnierle Barbara S, Wagner Ralf, Ralf Wagner, Thaler Sonja, Siegert, Sandra, Schnierle, Barbara, Siegert Sandra, Thaler, Sonja, Wagner, Ralf, Sonja Thaler   +11 more
core   +1 more source

Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]

, 2013
The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Mike Heilemann, Barbara Müller, Walter Muranyi (212637), Malkusch, Sebastian, Müller, Barbara, Hans-Georg Kräusslich (7273), Walter Muranyi, Mike Heilemann (162287), Barbara Müller (212640), Sebastian Malkusch (383895), Muranyi, Walter, Hans-Georg Kräusslich, Kräusslich, Hans-Georg, Sebastian Malkusch, Heilemann, Mike   +14 more
core   +2 more sources

A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]

, 2008
Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie, Ayman Samman, Willett Brian J, Samman, Ayman, Logan Nicola, Brian J Willett, Samman Ayman, McMonagle, Elizabeth L., Hosie Margaret J, Logan, Nicola, McMonagle Elizabeth L, Nicola Logan, Hosie, Margaret J., Willett, Brian J., Elizabeth L McMonagle   +14 more
core   +1 more source

Selective expansion of viral variants following experimental transmission of a reconstituted feline immunodeficiency virus quasispecies [PDF]

, 2013
Following long-term infection with virus derived from the pathogenic GL8 molecular clone of feline immunodeficiency virus (FIV), a range of viral variants emerged with distinct modes of interaction with the viral receptors CD134 and CXCR4, and ...
Margaret J Hosie, Martin Kraase (276419), McMonagle Elizabeth, Kraase, M., Varela, M., Mariana Varela (81646), Kraase Martin, Nicola Logan (276420), Mariana Varela, Hosie Margaret J., Brian J Willett, Brian J. Willett (276418), Logan Nicola, Elizabeth McMonagle (276421), Willett Brian J., Hosie, M.J., Varela Mariana, Nicola Logan, Logan, N., Willett, B.J., McMonagle, E., Margaret J. Hosie (276422), Elizabeth McMonagle, Martin Kraase   +23 more
core   +1 more source

Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody [PDF]

, 2010
<b>BACKGROUND:</b> In the acute phase of infection with feline immunodeficiency virus (FIV), the virus targets activated CD4+ T cells by utilising CD134 (OX40) as a primary attachment receptor and CXCR4 as a co-receptor.
Brian J Willett, Margaret J Hosie, Ayman Samman, McMonagle, Elizabeth L., Logan, Nicola, Nicola Logan, Hosie, Margaret J., Samman, Ayman, Willett, Brian J., Kraase, Martin, Martin Kraase, Elizabeth L McMonagle   +11 more
core   +1 more source

Upregulation of surface feline CXCR4 expression following ectopic expression of CCR5: implications for studies of the cell tropism of feline immunodeficiency virus [PDF]

, 2002
Feline CXCR4 and CCR5 were expressed in feline cells as fusion proteins with enhanced green fluorescent protein (EGFP). Expression of the EGFP fusion proteins was localized to the cell membrane, and surface expression of CXCR4 was confirmed by using a ...
Hosie, M.J., Willett, B.J., Cannon, C.A.
core   +1 more source

Molecular footprint of drug-selective pressure in a human immunodeficiency virus transmission chain [PDF]

, 2005
Known human immunodeficiency virus (HIV) transmission histories are invaluable models for investigating the evolutionary and transmission dynamics of the virus and to assess the accuracy of phylogenetic reconstructions.
A.-M. Vandamme, Lemey, P, A. Rambaut, Dumont, Stephanie, S. Dumont, Van Wijngaerden, Eric, Vandamme, A M, K. Van Laethem, Rambaut, Andrew, Vermeulen, Steve, S. Vermeulen, E. Van Wijngaerden, Dumont, S, Vandamme, Anne-Mieke, P. Lemey, Rambaut, A, Van Laethem, Kristel, Lemey, Philippe, I. Derdelinckx, Van Wijngaerden, E, Derdelinckx, Inge, Vermeulen, S, Van Laethem, K, Derdelinckx, I   +23 more
core   +1 more source