Results 1 to 10 of about 141,462 (202)
Protein self-association is a biologically remarkable event that involves and affects the structural and functional properties of proteins [...]
Gotte, Giovanni, Menegazzi, Marta
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Introduction: Cholinergic Receptor Muscarinic 1 (CHRM1) is a G protein-coupled acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex.
Mohammad Golam Sabbir +8 more
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Characterization of Hantavirus N Protein Intracellular Dynamics and Localization
Hantaviruses are enveloped viruses that possess a tri-segmented, negative-sense RNA genome. The viral S-segment encodes the multifunctional nucleocapsid protein (N), which is involved in genome packaging, intracellular protein transport, immunoregulation,
Robert-William Welke +9 more
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Insights from the Structure of an Active Form of Bacillus thuringiensis Cry5B
The crystal protein Cry5B, a pore-forming protein produced by the soil bacterium Bacillus thuringiensis, has been demonstrated to have excellent anthelmintic activity.
Jiaxin Li +4 more
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Structural basis of IRGB10 oligomerization by GTP hydrolysis
Immunity-related GTPase B10 (IRGB10) is a crucial member of the interferon (IFN)-inducible GTPases and plays a vital role in host defense mechanisms.
Hyun Ji Ha +8 more
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Overoxidation and Oligomerization of Trypanosoma cruzi Cytosolic and Mitochondrial Peroxiredoxins
Peroxiredoxins (Prxs) have been shown to be important enzymes for trypanosomatids, counteracting oxidative stress and promoting cell infection and intracellular survival.
María Dolores Piñeyro +4 more
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Drp1 is a central player in mitochondrial fission and is recruited to mitochondria by Mff and MIEFs (MIEF1 and MIEF2), but little is known about how its assembly state affects Drp1 mitochondrial recruitment and fission.
Rong Yu +6 more
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For highly pathogenic viruses, reporter assays that can be rapidly performed are critically needed to identify potentially functional mutations for further study under maximal containment (e.g., biosafety level 4 [BSL-4]).
Aaron E. Lin +13 more
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Vibrio cholerae cytolysin (VCC) is a β-barrel pore-forming toxin (β-PFT). Upon encountering the target cells, VCC forms heptameric β-barrel pores and permeabilizes the cell membranes.
Mahendra Singh +3 more
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Concentration‐dependent oligomerization and oligomeric arrangement of LptA [PDF]
AbstractGram‐negative bacteria such as Escherichia coli have an inner membrane and an asymmetric outer membrane (OM) that together protect the cytoplasm and act as a highly selective permeability barrier. Lipopolysaccharide (LPS) is the major component of the outer leaflet of the OM and is essential for the survival of nearly all Gram‐negative bacteria.
Jacqueline A, Merten +2 more
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