Results 1 to 10 of about 141,462 (202)

Protein Oligomerization

open access: yesInternational Journal of Molecular Sciences, 2023
Protein self-association is a biologically remarkable event that involves and affects the structural and functional properties of proteins [...]
Gotte, Giovanni, Menegazzi, Marta
openaire   +3 more sources

Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer’s disease

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Cholinergic Receptor Muscarinic 1 (CHRM1) is a G protein-coupled acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex.
Mohammad Golam Sabbir   +8 more
doaj   +1 more source

Characterization of Hantavirus N Protein Intracellular Dynamics and Localization

open access: yesViruses, 2022
Hantaviruses are enveloped viruses that possess a tri-segmented, negative-sense RNA genome. The viral S-segment encodes the multifunctional nucleocapsid protein (N), which is involved in genome packaging, intracellular protein transport, immunoregulation,
Robert-William Welke   +9 more
doaj   +1 more source

Insights from the Structure of an Active Form of Bacillus thuringiensis Cry5B

open access: yesToxins, 2022
The crystal protein Cry5B, a pore-forming protein produced by the soil bacterium Bacillus thuringiensis, has been demonstrated to have excellent anthelmintic activity.
Jiaxin Li   +4 more
doaj   +1 more source

Structural basis of IRGB10 oligomerization by GTP hydrolysis

open access: yesFrontiers in Immunology, 2023
Immunity-related GTPase B10 (IRGB10) is a crucial member of the interferon (IFN)-inducible GTPases and plays a vital role in host defense mechanisms.
Hyun Ji Ha   +8 more
doaj   +1 more source

Overoxidation and Oligomerization of Trypanosoma cruzi Cytosolic and Mitochondrial Peroxiredoxins

open access: yesPathogens, 2023
Peroxiredoxins (Prxs) have been shown to be important enzymes for trypanosomatids, counteracting oxidative stress and promoting cell infection and intracellular survival.
María Dolores Piñeyro   +4 more
doaj   +1 more source

The Molecular Assembly State of Drp1 Controls its Association With the Mitochondrial Recruitment Receptors Mff and MIEF1/2

open access: yesFrontiers in Cell and Developmental Biology, 2021
Drp1 is a central player in mitochondrial fission and is recruited to mitochondria by Mff and MIEFs (MIEF1 and MIEF2), but little is known about how its assembly state affects Drp1 mitochondrial recruitment and fission.
Rong Yu   +6 more
doaj   +1 more source

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

open access: yesViruses, 2020
For highly pathogenic viruses, reporter assays that can be rapidly performed are critically needed to identify potentially functional mutations for further study under maximal containment (e.g., biosafety level 4 [BSL-4]).
Aaron E. Lin   +13 more
doaj   +1 more source

Curcumin Inhibits Membrane-Damaging Pore-Forming Function of the β-Barrel Pore-Forming Toxin Vibrio cholerae Cytolysin

open access: yesFrontiers in Microbiology, 2022
Vibrio cholerae cytolysin (VCC) is a β-barrel pore-forming toxin (β-PFT). Upon encountering the target cells, VCC forms heptameric β-barrel pores and permeabilizes the cell membranes.
Mahendra Singh   +3 more
doaj   +1 more source

Concentration‐dependent oligomerization and oligomeric arrangement of LptA [PDF]

open access: yesProtein Science, 2011
AbstractGram‐negative bacteria such as Escherichia coli have an inner membrane and an asymmetric outer membrane (OM) that together protect the cytoplasm and act as a highly selective permeability barrier. Lipopolysaccharide (LPS) is the major component of the outer leaflet of the OM and is essential for the survival of nearly all Gram‐negative bacteria.
Jacqueline A, Merten   +2 more
openaire   +2 more sources

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