Results 41 to 50 of about 141,462 (202)
Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA
mBio, 2019 The formation of multimerized protein assemblies has emerged as a core component of immune signal amplification, yet the biochemical basis of this phenomenon remains unclear for many mammalian proteins within host defense pathways.
Krystal K. Lum +3 more
doaj +1 more source
Pathogens, 2020 The Ebola virus (EBOV) harbors seven genes, one of which is the matrix protein eVP40, a peripheral protein that is sufficient to induce the formation of virus-like particles from the host cell plasma membrane.
Kristen A. Johnson +5 more
doaj +1 more source
Activation and Oligomerization of Aspartylglucosaminidase [PDF]
Journal of Biological Chemistry, 1998 Secretory, membrane, and lysosomal proteins undergo covalent modifications and acquire their secondary and tertiary structure in the lumen of the endoplasmic reticulum (ER). In order to pass the ER quality control system and become transported to their final destinations, many of them are also assembled into oligomers.
J, Saarela +6 more
openaire +2 more sources
Oligomerization of 3,5-Dimethyl Benzyl Alcohol Promoted by Clay: Experimental and Theoretical Study
Molecules, 2010 Linear oligomerization of 3,5-dimethyl benzyl alcohol is induced by a montmorillonite clay (Tonsil Optimum Extra), producing 1,3,5,7-tetramethyl-9,10-dihydro-anthracene, which, by loss of protons results in the product 1,3,5,7-tetramethylanthracene.
Manuel Salmón +5 more
doaj +1 more source
Molecules, 2019 G protein-coupled receptors (GPCRs) are involved in a wide variety of physiological processes. Therefore, approximately 40% of currently prescribed drugs have targeted this receptor family.
Metehan Ilter +2 more
doaj +1 more source
eLife, 2020 Septin proteins evolved from ancestral GTPases and co-assemble into hetero-oligomers and cytoskeletal filaments. In Saccharomyces cerevisiae, five septins comprise two species of hetero-octamers, Cdc11/Shs1–Cdc12–Cdc3–Cdc10–Cdc10–Cdc3–Cdc12–Cdc11/Shs1 ...
Courtney R Johnson +6 more
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What’s the Defect? Using Mass Defects to Study Oligomerization of Membrane Proteins and Peptides in Nanodiscs with Native Mass Spectrometry [PDF]
, 2023 Many membrane proteins form functional complexes that are either homo- or hetero-oligomeric. However, it is challenging to characterize membrane protein oligomerization in intact lipid bilayers, especially for polydisperse mixtures.
Michael, Marty, Julia, Townsend
core +1 more source
Membranes, 2021 Caveolins are critical for the formation of caveolae, which are small invaginations of the plasma membrane involved in a variety of biological processes.
Hae-Jun Park +8 more
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Учёные записки Казанского университета: Серия Физико-математические науки, 2020 In this work, we studied the diversity of silicic acid oligomers with Sin=(3−8) obtained during molecular dynamics in a reaction Feston–Garofalini force field that describes the process of oligomerization of silicic acids in an aqueous solution at the ...
E.D. Izotova +2 more
doaj +1 more source
Antibodies, 2018 The pore-forming epsilon toxin (ETX) produced by Clostridium perfringens is among the most lethal bacterial toxins known. Sensitive antibody-based reagents are needed to detect toxin, distinguish mechanisms of cell death, and prevent ETX toxicity.
Jennifer R. Linden +10 more
doaj +1 more source