Results 21 to 30 of about 141,462 (202)
Frontiers in Immunology, 2021 The increase in confirmed COVID-19 cases and SARS-CoV-2 variants calls for the development of safe and broad cross-protective vaccines. The RBD of the spike protein was considered to be a safe and effective candidate antigen.
Jintao Zou +14 more
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Rethinking Leucine Zipper : ribonuclease activity and structural dynamics of a ubiquitous oligomerization motif [PDF]
, 2011 This dissertation focuses on structural, dynamic and catalytic properties of a Leucine Zipper (LZ) motif – a family of protein oligomerization domains which belong to the structural class of coiled coil proteins.
Nikolaev, Yaroslav
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Exploring the Oligomerization of Nav1.5 and Its Implication for the Dominant-Negative Effect [PDF]
, 2023 Clusters of the α-subunit of voltage-gated sodium (Nav) channels have been observed in various tissues and are recognized as key regulators of cellular excitability and action potential propagation.
Iamshanova, Oksana +2 more
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, 2014 The chapter is a wide overview focused on protein oligomerization, a topic that definitely increased its importance in the last decades because of its connection to protein structure(s) and activity(ies).
LIBONATI, Massimo, GOTTE, Giovanni
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Fluorescence fluctuation analysis of Arabidopsis thaliana somatic embryogenesis receptor-like kinase and brassinosteroid insensitive 1 receptor ologomerization. [PDF]
, 2008 Receptor kinases play a key role in the cellular perception of signals. To verify models for receptor activation through dimerization, an experimental system is required to determine the precise oligomerization status of proteins within living cells ...
Vries, S.C., de +15 more
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New bifunctional Ni H-Beta catalysts for the heterogeneous oligomerization of ethylene [PDF]
, 2013 [EN] The development of sustainable active and stable heterogeneous catalysts for the oligomerization of ethylene to replace the unfriendly homogenous systems based on transition metal complexes currently applied in the industry still remains a ...
Arribas Viana, Maria De Los Desamparados +3 more
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eLife, 2019 APOBEC3G (A3G), an enzyme expressed in primates with the potential to inhibit human immunodeficiency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with two domains, a catalytically active, weakly ssDNA binding ...
Michael Morse +5 more
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ASC filament formation serves as a signal amplification mechanism for inflammasomes [PDF]
, 2016 A hallmark of inflammasome activation is the ASC speck, a micrometre-sized structure formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD), which consists of a pyrin domain (PYD) and a caspase ...
Hiller, Sebastian +4 more
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Biomolecules, 2023 In a previous study, we demonstrated that the Clostridioides difficile VirB4-like ATPase forms oligomers in vitro. In the current investigation, to study the observed phenomenon in more detail, we prepared a library of VirB4-derived peptides (delVirB4s ...
Julya Sorokina +7 more
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Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs [PDF]
, 2016 The formation of small Aβ42 oligomers has been implicated as a toxic species in Alzheimer disease (AD). In strong support of this hypothesis we found that overexpression of Yap1802, the yeast ortholog of the human AD risk factor, phosphatidylinositol ...
Maria Valencik +10 more
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