Results 11 to 20 of about 141,462 (202)
Oligomerization of daptomycin on membranes [PDF]
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2011 Daptomycin is a lipopeptide antibiotic that kills Gram-positive bacteria by membrane depolarization. While it has long been assumed that the mode of action of daptomycin involves the formation of membrane-associated oligomers, this has so far not been experimentally demonstrated.
Muraih, Jawad K. +3 more
openaire +3 more sources
What are oligomerization domains good for?
, 2000 Collagen triple helices, coiled coils and other oligomerization domains mediate the subunit assembly of a large number of proteins. Oligomerization leads to functional advantages of multivalency and high binding strength, increased structure ...
Engel, Jürgen, Kammerer, Richard A.
core +10 more sources
First Principles Analysis of Ethylene Oligomerization on Single-site Ga3+ Catalysts Supported on Amorphous Silica [PDF]
, 2021 Amorphous, single site, silica-supported main group metal catalysts have recently been found to promote olefin oligomerization with high activity at moderate temperatures and pressures (~250°C and 1 atm).
Yinan, Xu +4 more
core +2 more sources
, 2021 GPCR oligomerization plays a critical role in cellular signaling, yet the stoichiometry of the interactions between oligomers and binding ligands in living cells remains a longstanding challenge.
Hua He (120374) +19 more
core +1 more source
Biomolecules, 2022 Homomultimerization of MT1-MMP (membrane type 1 matrix metalloproteinase) through the hemopexin, transmembrane, and cytoplasmic domains plays a very important role in the activation of proMMP-2 and the degradation of pericellular collagen.
Marton Fogarasi, Simona Dima
doaj +1 more source
GPCR-OKB: the G protein coupled receptor oligomer knowledge base [PDF]
, 2010 Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically.
Bas Vroling +57 more
core +3 more sources
Cosolute modulation of protein oligomerization reactions in the homeostatic timescale
, 2021 Protein oligomerization processes are widespread and of crucial importance to understand degenerative diseases and healthy regulatory pathways. One particular case is the homo-oligomerization of folded domains involving domain swapping, often found as a ...
0000-0002-0310-4943 +14 more
core +1 more source
Molecular Perspectives for mu/delta Opioid Receptor Heteromers as Distinct, Functional Receptors
Cells, 2014 Opioid receptors are the sites of action for morphine and the other opioid drugs. Abundant evidence now demonstrates that different opioid receptor types can physically associate to form heteromers.
Edmund W. Ong, Catherine M. Cahill
doaj +1 more source
Molecular and Kinetic Models for Pore Formation of Bacillus thuringiensis Cry Toxin
Toxins, 2022 Cry proteins from Bacillus thuringiensis (Bt) and other bacteria are pesticidal pore-forming toxins. Since 2010, when the ABC transporter C2 (ABCC2) was identified as a Cry1Ac protein resistant gene, our understanding of the mode of action of Cry protein
Haruka Endo
doaj +1 more source
Targeting the oligomerization of BCR/ABL by membrane permeable competitive peptides inhibits the proliferation of Philadelphia Chromosome positive leukemic cells [PDF]
, 2013 The BCR/ABL fusion protein is the hallmark of Philadelphia Chromosome positive (Ph+) leukemia. The constitutive activation of the ABL-kinase in BCR/ABL cells induces the leukemic phenotype.
Mahajna, Jamal +8 more
core +1 more source