Results 51 to 60 of about 133,297 (213)

Oligomeric ferrocene rings

open access: yesNature Chemistry, 2016
Cyclic oligomers comprising strongly interacting redox-active monomer units represent an unknown, yet highly desirable class of nanoscale materials. Here we describe the synthesis and properties of the first family of molecules belonging to this compound category-differently sized rings comprising only 1,1'-disubstituted ferrocene units (cyclo[n], n ...
Michael S. Inkpen   +6 more
openaire   +4 more sources

Orientation and Oligomerization Specificity of the Bcr Coiled-Coil Oligomerization Domain [PDF]

open access: yesBiochemistry, 2005
The Bcr oligomerization domain, from the Bcr-Abl oncoprotein, is an attractive therapeutic target for treating leukemias because it is required for cellular transformation. The domain homodimerizes via an antiparallel coiled coil with an adjacent short, helical swap domain.
Christina M, Taylor, Amy E, Keating
openaire   +2 more sources

Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer’s disease

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: Cholinergic Receptor Muscarinic 1 (CHRM1) is a G protein-coupled acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex.
Mohammad Golam Sabbir   +8 more
doaj   +1 more source

Kaede for Detection of Protein Oligomerization [PDF]

open access: yesMolecular Plant, 2013
Photoconvertible fluorescent proteins such as Kaede are routinely used for tracking proteins, organelles, and whole cells. Kaede was the first identified photoconvertible fluorescent protein and has since become the most commonly used photoconvertible fluorescent protein in vertebrates.
Wolf, Heike   +3 more
openaire   +3 more sources

Characterization of Hantavirus N Protein Intracellular Dynamics and Localization

open access: yesViruses, 2022
Hantaviruses are enveloped viruses that possess a tri-segmented, negative-sense RNA genome. The viral S-segment encodes the multifunctional nucleocapsid protein (N), which is involved in genome packaging, intracellular protein transport, immunoregulation,
Robert-William Welke   +9 more
doaj   +1 more source

The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer

open access: yesIUCrJ, 2020
Neisseria meningitidis is carried by nearly a billion humans, causing developmental impairment and over 100 000 deaths a year. A quinol-dependent nitric oxide reductase (qNOR) plays a critical role in the survival of the bacterium in the human host.
M. Arif M. Jamali   +8 more
doaj   +1 more source

Insights from the Structure of an Active Form of Bacillus thuringiensis Cry5B

open access: yesToxins, 2022
The crystal protein Cry5B, a pore-forming protein produced by the soil bacterium Bacillus thuringiensis, has been demonstrated to have excellent anthelmintic activity.
Jiaxin Li   +4 more
doaj   +1 more source

The Structure of the Oligomerization Domain of Lsr2 from Mycobacterium tuberculosis Reveals a Mechanism for Chromosome Organization and Protection

open access: yes, 2012
Lsr2 is a small DNA-binding protein present in mycobacteria and related actinobacteria that regulates gene expression and influences the organization of bacterial chromatin.
Isabel Usón (319527)   +32 more
core   +1 more source

Sulfatide-Hsp70 Interaction Promotes Hsp70 Clustering and Stabilizes Binding to Unfolded Protein

open access: yesBiomolecules, 2015
The 70-kDa heat shock protein (Hsp70), one of the major stress-inducible molecular chaperones, is localized not only in the cytosol, but also in extracellular milieu in mammals. Hsp70 interacts with various cell surface glycolipids including sulfatide (3'
Yoichiro Harada   +2 more
doaj   +1 more source

A Quinolinone Compound Inhibiting the Oligomerization of Nucleoprotein of Influenza A Virus Prevents the Selection of Escape Mutants

open access: yesViruses, 2020
The emergence of resistance to currently available anti-influenza drugs has heightened the need for antivirals with novel mechanisms of action. The influenza A virus (IAV) nucleoprotein (NP) is highly conserved and essential for the formation of viral ...
Juliann Nzembi Makau   +6 more
doaj   +1 more source

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