Results 51 to 60 of about 141,462 (202)

Effects of Serine or Threonine in the Active Site of Typical 2-Cys Prx on Hyperoxidation Susceptibility and on Chaperone Activity

open access: yesAntioxidants, 2021
Typical 2-Cys peroxiredoxins (2-Cys Prx) are ubiquitous Cys-based peroxidases, which are stable as decamers in the reduced state, and may dissociate into dimers upon disulfide bond formation.
Carlos A. Tairum   +9 more
doaj   +1 more source

Oligomerization of Hsp70: Current Perspectives on Regulation and Function

open access: yesFrontiers in Molecular Biosciences, 2019
The Hsp70 molecular chaperone in conjunction with Hsp90 and a suite of helper co-chaperones are required for the folding and subsequent refolding of a large proportion of the proteome.
Jade E. Takakuwa   +3 more
doaj   +1 more source

Oligomer formation of SARS-CoV-2 ORF8 through 73YIDI76 motifs regulates immune response and non-infusion antiviral interactions

open access: yesFrontiers in Molecular Biosciences, 2023
Introduction: Open Reading Frame 8 (ORF8) is a 121 amino acid length SARS-CoV-2 specific accessory protein that plays crucial roles in viral infectivity, and pathogenesis.
Mohammad Assadizadeh   +1 more
doaj   +1 more source

Control of Protein Oligomerization and De-oligomerization on Lipid Membranes [PDF]

open access: yes, 2014
Oligomerization of protein into amyloid fibrils is central to the pathogenesis of several neurodegenerative disorders. Amyloid fibrillation and the cytotoxic actions of amyloids are membrane-associated processes.
Mahalka, Ajay
core   +1 more source

Oligomerization of C2-C4 Hydrocarbons in the Presence of Ruthenium-Nickel Supported Catalysts

open access: yesBulletin of Chemical Reaction Engineering & Catalysis, 2016
The oligomerization of C2-C4 light hydrocarbon gasses in the presence of ruthenium and nickel supported catalysts is investigated. Determined selectivity of the catalysts by isooctane.
Raila Toktassyn   +3 more
doaj   +1 more source

Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein

open access: yesFrontiers in Neuroscience, 2021
α-synuclein (αSyn) is the main protein component of Lewy bodies, intracellular inclusions found in the brain of Parkinson’s disease (PD) patients. Neurotoxic αSyn species are broadly modified post-translationally and, in patients with genetic forms of PD,
Ana Martinez Hernandez   +16 more
doaj   +1 more source

Minimal Yet Powerful: The Role of Archaeal Small Heat Shock Proteins in Maintaining Protein Homeostasis

open access: yesFrontiers in Molecular Biosciences, 2022
Small heat shock proteins (sHsp) are a ubiquitous group of ATP-independent chaperones found in all three domains of life. Although sHsps in bacteria and eukaryotes have been studied extensively, little information was available on their archaeal homologs
Mousam Roy   +2 more
doaj   +1 more source

Modern methods to investigate the oligomerization of glycoprotein hormone receptors (TSHR, LHR, FSHR)

open access: yes, 2013
As for other GPCRs, the oligomerization of glycoprotein hormone receptors (GPHRs) appears as critical event for receptor function. By means of modern techniques based on the BRET or FRET principle, GPHR oligomerization has been reported to explain ...
Luca Persani   +3 more
core   +1 more source

A small bioactive glycoside inhibits epsilon toxin and prevents cell death

open access: yesDisease Models & Mechanisms, 2019
Clostridium perfringens epsilon toxin (Etx) is categorized as the third most lethal bioterrorism agent by the Centers for Disease Control and Prevention (CDC), with no therapeutic counter measures available for humans.
Abhishek Shivappagowdar   +11 more
doaj   +1 more source

Oligomerization of higher olefins [PDF]

open access: yes, 2010
Includes abstract.Includes bibliographical references.A series of new substituted cyclopentadienyl ligands and their chromium complexes were successfully synthesised and characterised using a wide range of analytical and spectroscopic techniques such as ...
Kekana, Lizzy Mpho
core   +1 more source

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