Results 11 to 20 of about 2,522,803 (297)

Tetraspanin Assemblies in Virus Infection [PDF]

open access: yesFrontiers in Immunology, 2018
Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma membrane "master organizers." They form Tspan-enriched microdomains (TEMs or TERMs) through lateral association with one another and other membrane proteins. If multiple microdomains associate with each other, larger platforms can form.
Florin, Luise, Lang, Thorsten
openaire   +4 more sources

Electrostatics and the assembly of an RNA virus [PDF]

open access: yesPhysical Review E, 2005
Electrostatic interactions play a central role in the assembly of single-stranded RNA viruses. Under physiological conditions of salinity and acidity, virus capsid assembly requires the presence of genomic material that is oppositely charged to the core proteins. In this paper we apply basic polymer physics and statistical mechanics methods to the self-
Schoot, van der, P.P.A.M., Bruinsma, R.
openaire   +3 more sources

Alphavirus Particles Can Assemble with an Alternate Triangulation Number

open access: yesViruses, 2022
Alphaviruses are spherical, enveloped RNA viruses primarily transmitted by mosquitoes, and cause significant arthritogenic and neurotropic disease in humans and livestock.
Jason T. Kaelber   +3 more
doaj   +1 more source

Mutation of Hydrophobic Residues in the C-Terminal Domain of the Marburg Virus Matrix Protein VP40 Disrupts Trafficking to the Plasma Membrane

open access: yesViruses, 2020
Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the host ...
Kaveesha J. Wijesinghe   +7 more
doaj   +1 more source

RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]

open access: yes, 2012
Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
core   +6 more sources

Live Cell Imaging Reveals HBV Capsid Translocation from the Nucleus To the Cytoplasm Enabled by Cell Division

open access: yesmBio, 2023
Hepatitis B virus (HBV) capsid assembly is traditionally thought to occur predominantly in the cytoplasm, where the virus gains access to the virion egress pathway.
Sofia Romero   +5 more
doaj   +1 more source

Three-Dimensional Investigations of Virus-Associated Structures in the Nuclei with White Spot Syndrome Virus (WSSV) Infection in Red Swamp Crayfish (Procambarus clarkii)

open access: yesAnimals, 2022
White spot syndrome virus (WSSV) has been reported to cause severe economic loss in the shrimp industry. With WSSV being a large virus still under investigation, the 3D structure of its assembly remains unclear.
Yovita Permata Budi   +4 more
doaj   +1 more source

Virus assembly, allostery and antivirals [PDF]

open access: yesTrends in Microbiology, 2011
Assembly of virus capsids and surface proteins must be regulated to ensure that the resulting complex is an infectious virion. In this review, we examine assembly of virus capsids, focusing on hepatitis B virus and bacteriophage MS2, and formation of glycoproteins in the alphaviruses.
Zlotnick, Adam, Mukhopadhyay, Suchetana
openaire   +2 more sources

Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures

open access: yesViruses, 2023
The formation of many double-stranded DNA viruses, such as herpesviruses and bacteriophages, begins with the scaffolding-protein-mediated assembly of the procapsid. Subsequently, the procapsid undergoes extensive structural rearrangement and expansion to
Hao Xiao   +7 more
doaj   +1 more source

The interaction between herpes simplex virus 1 genome and promyelocytic leukemia nuclear bodies (PML-NBs) as a hallmark of the entry in latency

open access: yesMicrobial Cell, 2016
Herpes simplex virus 1 (HSV-1) is a human pathogen that establishes latency in the nucleus of infected neurons in the PNS and the CNS. At the transcriptional level latency is characterized by a quasi-complete silencing of the extrachromosomal viral ...
Patrick Lomonte
doaj   +1 more source

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