Results 11 to 20 of about 262,059 (309)
Mechanisms of Virus Assembly [PDF]
Annual Review of Physical Chemistry, 2015 Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review summarizes the physics that govern the processes by which capsids assemble within their host cells and in vitro.
Perlmutter, Jason D, Hagan, Michael F
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Tetraspanin Assemblies in Virus Infection [PDF]
Frontiers in Immunology, 2018 Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma membrane "master organizers." They form Tspan-enriched microdomains (TEMs or TERMs) through lateral association with one another and other membrane proteins. If multiple microdomains associate with each other, larger platforms can form.
Florin, Luise, Lang, Thorsten
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Electrostatics and the assembly of an RNA virus [PDF]
Physical Review E, 2005 Electrostatic interactions play a central role in the assembly of single-stranded RNA viruses. Under physiological conditions of salinity and acidity, virus capsid assembly requires the presence of genomic material that is oppositely charged to the core proteins. In this paper we apply basic polymer physics and statistical mechanics methods to the self-
Schoot, van der, P.P.A.M., Bruinsma, R.
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Animals, 2022 White spot syndrome virus (WSSV) has been reported to cause severe economic loss in the shrimp industry. With WSSV being a large virus still under investigation, the 3D structure of its assembly remains unclear.
Yovita Permata Budi +4 more
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Viruses, 2023 The formation of many double-stranded DNA viruses, such as herpesviruses and bacteriophages, begins with the scaffolding-protein-mediated assembly of the procapsid. Subsequently, the procapsid undergoes extensive structural rearrangement and expansion to
Hao Xiao +7 more
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Microbial Cell, 2016 Herpes simplex virus 1 (HSV-1) is a human pathogen that establishes latency in the nucleus of infected neurons in the PNS and the CNS. At the transcriptional level latency is characterized by a quasi-complete silencing of the extrachromosomal viral ...
Patrick Lomonte
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The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]
, 2008 Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F. +23 more
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Virus assembly, allostery and antivirals [PDF]
Trends in Microbiology, 2011 Assembly of virus capsids and surface proteins must be regulated to ensure that the resulting complex is an infectious virion. In this review, we examine assembly of virus capsids, focusing on hepatitis B virus and bacteriophage MS2, and formation of glycoproteins in the alphaviruses.
Zlotnick, Adam, Mukhopadhyay, Suchetana
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Efficient support of virus-like particle assembly by the HIV-1 packaging signal
eLife, 2018 The principal structural component of a retrovirus particle is the Gag protein. Retroviral genomic RNAs contain a ‘packaging signal’ (‘Ψ') and are packaged in virus particles with very high selectivity.
Mauricio Comas-Garcia +5 more
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Dynamics of HIV-1 assembly and release. [PDF]
, 2009 Assembly and release of human immunodeficiency virus (HIV) occur at the plasma membrane of infected cells and are driven by the Gag polyprotein. Previous studies analyzed viral morphogenesis using biochemical methods and static images, while dynamic and ...
Kräusslich Hans-Georg +28 more
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