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Endophilin mediated endocytosis and epidermal growth factor receptor govern Japanese encephalitis virus entry and infection in neuronal cells. [PDF]
PLoS PathogensSeveral trafficking pathways are operational at the plasma membrane, and both clathrin-dependent, and clathrin-independent endocytosis (CIE), can serve as virus entry portals.
Puja Sharma +10 more
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A multi-glycoprotein synergized recombinant virus system resolved the research dilemma of Epstein-Barr virus entry and facilitated the development of entry-specific drugs or vaccines [PDF]
Current Research in Microbial SciencesEpstein-Barr virus (EBV) causes multiple severe diseases, and its entry process is a promising prophylactic and therapeutic target. However, EBV entry is intricate with several unresolved mechanisms, and current research methods for it is limited ...
Tianyu Lu +12 more
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Competitive Cooperation of Hemagglutinin and Neuraminidase during Influenza A Virus Entry
Viruses, 2019 The hemagglutinin (HA) and neuraminidase (NA) of influenza A virus possess antagonistic activities on interaction with sialic acid (SA), which is the receptor for virus attachment.
Ruikun Du, Qinghua Cui, Lijun Rong
doaj +3 more sources
Viruses, 2021 To establish a productive infection in host cells, viruses often use one or multiple host membrane glycoproteins as their receptors. For Influenza A virus (IAV) such a glycoprotein receptor has not been described, to date.
Shah Kamranur Rahman +10 more
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Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains
mBio, 2021 Selective pressures drive adaptive changes in the coronavirus spike proteins directing virus-cell entry. These changes are concentrated in the amino-terminal domains (NTDs) and the receptor-binding domains (RBDs) of complex modular spike protein trimers.
Enya Qing +6 more
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mBio, 2022 The lipid composition of the host cell membrane is one of the key determinants of the entry of enveloped viruses into cells. To elucidate the detailed mechanisms behind the cell entry of rubella virus (RuV), one of the enveloped viruses, we searched for ...
Yoshio Mori +10 more
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Different infectivity of HIV-1 strains is linked to number of envelope trimers required for entry. [PDF]
PLoS Pathogens, 2015 HIV-1 enters target cells by virtue of envelope glycoprotein trimers that are incorporated at low density in the viral membrane. How many trimers are required to interact with target cell receptors to mediate virus entry, the HIV entry stoichiometry ...
Oliver F Brandenberg +4 more
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Heparan Sulfate Binding Cationic Peptides Restrict SARS-CoV-2 Entry
Pathogens, 2021 A novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic. While the world is striving for a treatment modality against SARS-CoV-2, our understanding about the virus entry mechanisms may help to design entry ...
Rahul K. Suryawanshi +5 more
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Encephalomyocarditis Virus Entry Unveiled
mBio, 2019 Picornaviruses are a widespread group of pathogens that can cause diverse pathologies. Pathogenesis is thought to be driven by the tissue-specific tropisms displayed by these viruses.
Sara Cherry
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Viruses, 2019 Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. It is transmitted enterically but replicates in the liver. Recent studies indicate that HEV exists in two forms: naked, nonenveloped virions that are shed into feces to ...
Xin Yin, Zongdi Feng
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