Results 41 to 50 of about 2,750,709 (301)
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus.
PLoS Pathogens, 2008 The phosphoinositide-3 kinase (PI3K) pathway regulates diverse cellular activities related to cell growth, migration, survival, and vesicular trafficking. It is known that Ebola virus requires endocytosis to establish an infection.
Mohammad F Saeed +4 more
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Zika virus: mapping and reprogramming the entry [PDF]
Cell Communication and Signaling, 2019 The flaviviridae family comprises single-stranded RNA viruses that enter cells via clathrin-mediated pH-dependent endocytosis. Although the initial events of the virus entry have been already identified, data regarding intracellular virus trafficking and delivery to the replication site are limited.
Katarzyna Owczarek +5 more
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Nectin-2 Acts as a Viral Entry Mediated Molecule That Binds to Human Herpesvirus 6B Glycoprotein B
Viruses, 2022 Human herpesvirus 6B (HHV-6B) is a T-lymphotropic virus and the etiological agent of exanthem subitum. HHV-6B is present in a latent or persistent form after primary infection and is produced in the salivary glands or transmitted to this organ.
Hirohito Ogawa +5 more
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Virus entry—an unwilling collaboration by the cell [PDF]
Current Opinion in Virology, 2013 How simple, lifeless particles such as viruses cause devastating diseases and epidemics that affect the everyday lives of most people remain incompletely understood despite intense research efforts. We have determined the genomic sequences of hundreds of viruses, analyzed their structures and composition, and probed their replication mechanisms.
Helenius Ari, Moss Bernard
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Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]
, 2010 The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J. +5 more
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VirusesBovine respiratory syncytial virus (BRSV) is an enveloped RNA virus that utilizes clathrin-mediated endocytosis for cell entry and is a significant pathogen in bovine respiratory disease (BRD).
Yang Liu +8 more
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Cell Biology of Virus Entry [PDF]
Cell, 2000 I thank many of the meeting participants for their help in preparing this review and for allowing me to quote their unpublished results. I am grateful to E. Berger, R. Blumenthal, R. Doms, H. Golding, L. Chernomordik, J. Cunningham, M. Kielian, and R. Lamb, whose comments improved the entire review. I am in debt to C.
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SnapShot: Enveloped Virus Entry
Cell, 2020 In order to initiate successful infection, viruses have to transmit and deliver their genome from one host cell or organism to another. To achieve this, enveloped viruses must first fuse their membrane with those of the target host cell. Here, we describe the sequence of events leading to the entry of representative enveloped viruses, highlighting the ...
Mercer, Jason +3 more
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Real-time tracking of vaccinia virus entry using a split luciferase complementation assay
Journal of VirologyA recombinant vaccinia virus (vA4-HiBiT) was constructed with a short, split luciferase HiBiT tag at the C-terminus of the A4 core protein open reading frame.
Yunliang Zhang +4 more
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, 1989 In addition to its many other functions, the plasma membrane of eukaryotic cells serves as a barrier against invading parasites and viruses. It is not permeable to ions and to low molecular weight solutes, let alone to proteins and polynucleotides. Yet it is clear that viruses are capable of transferring their genome and accessory proteins into the ...
Marsh, Mark, Helenius, Ari
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