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Virus Entry: Open Sesame [PDF]
Cell, 2006 Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells.
Marsh, Mark, Helenius, Ari
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Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus
Viruses, 2018 Ebola virus is the causative agent of Ebola virus disease in humans. The lethality of Ebola virus infection is about 50%, supporting the urgent need to develop anti-Ebola drugs.
Qinghua Cui +7 more
doaj +1 more source
A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]
, 2008 Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie +14 more
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Orthobunyavirus ultrastructure and the curious tripodal glycoprotein spike [PDF]
, 2013 The genus <i>Orthobunyavirus</i> within the family <i>Bunyaviridae</i> constitutes an expanding group of emerging viruses, which threaten human and animal health.
McLees, A. +36 more
core +1 more source
Cells, 2021 Research on infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is currently restricted to BSL-3 laboratories. SARS-CoV2 virus-like particles (VLPs) offer a BSL-1, replication-incompetent system that can be used to evaluate virus ...
Binod Kumar +5 more
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Analysis of Ebola Virus Entry Into Macrophages [PDF]
Journal of Infectious Diseases, 2015 Published by Oxford Univ. Press, Oxford [u.a.]
Dahlmann, Franziska +13 more
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Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions [PDF]
, 2007 Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus ...
Ralf Bartenschlager +17 more
core +1 more source
Viruses, 2023 Many viruses attach to host cells by first interacting with cell surface proteoglycans containing heparan sulfate (HS) glycosaminoglycan chains and then by engaging with specific receptor, resulting in virus entry.
Poonam Sharma +5 more
doaj +1 more source
Microtubules in Influenza Virus Entry and Egress [PDF]
Viruses, 2020 Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs. It is necessary to understand the detailed and complex interactions between influenza virus and its host cells in order to identify successful strategies for therapeutic intervention.
Caitlin Simpson, Yohei Yamauchi
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Ezrin interacts with the SARS coronavirus spike protein and restrains infection at the entry stage [PDF]
, 2012 © 2012 Millet et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Béatrice Nal +66 more
core +1 more source