Results 31 to 40 of about 325,771 (306)

Entry properties and entry inhibitors of a human H7N9 influenza virus. [PDF]

open access: yesPLoS ONE, 2014
The recently identified human infections with a novel avian influenza H7N9 virus in China raise important questions regarding possible risk to humans. However, the entry properties and tropism of this H7N9 virus were poorly understood.
Youhui Si   +10 more
doaj   +1 more source

Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. [PDF]

open access: yes, 2010
Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Roy, Polly   +3 more
core   +1 more source

A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells.

open access: yesPLoS ONE, 2010
Acid dependent infection of Hela and Vero cells by BTV-10 occurs from within early-endosomes following virus uptake by clathrin-mediated endocytosis (Forzan et al., 2007: J Virol 81: 4819-4827).
Sarah Gold   +3 more
doaj   +1 more source

Single virus tracking of Ebola virus entry through lipid rafts in living host cells

open access: yesBiosafety and Health, 2020
Ebola virus (EBOV) is one of the most pathogenic viruses in humans which can cause a lethal hemorrhagic fever. Understanding the cellular entry mechanisms of EBOV can promote the development of new therapeutic strategies to control virus replication and ...
Cong Jin   +9 more
doaj   +1 more source

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

open access: yes, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick   +38 more
core   +1 more source

Exploiting Herpes Simplex Virus Entry for Novel Therapeutics

open access: yesViruses, 2013
Herpes Simplex virus (HSV) is associated with a variety of diseases such as genital herpes and numerous ocular diseases. At the global level, high prevalence of individuals who are seropositive for HSV, combined with its inconspicuous infection, remains ...
Deepak Shukla, Satvik Hadigal
doaj   +1 more source

A capsid-encoded PPxY-motif facilitates adenovirus entry. [PDF]

open access: yes, 2010
Viruses use cellular machinery to enter and infect cells. In this study we address the cell entry mechanisms of nonenveloped adenoviruses (Ads). We show that protein VI, an internal capsid protein, is rapidly exposed after cell surface attachment and ...
Segura-Morales, Carolina   +28 more
core   +1 more source

Virus Entry: Open Sesame [PDF]

open access: yesCell, 2006
Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells.
Marsh, Mark, Helenius, Ari
openaire   +3 more sources

HCMV spread and cell tropism are determined by distinct virus populations. [PDF]

open access: yes, 2011
Human cytomegalovirus (HCMV) can infect many different cell types in vivo. Two gH/gL complexes are used for entry into cells. gH/gL/pUL(128,130,131A) shows no selectivity for its host cell, whereas formation of a gH/gL/gO complex only restricts the ...
Ulrich H Koszinowski   +10 more
core   +1 more source

Identification of Diaryl-Quinoline Compounds as Entry Inhibitors of Ebola Virus

open access: yesViruses, 2018
Ebola virus is the causative agent of Ebola virus disease in humans. The lethality of Ebola virus infection is about 50%, supporting the urgent need to develop anti-Ebola drugs.
Qinghua Cui   +7 more
doaj   +1 more source

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