Results 51 to 60 of about 325,771 (306)
A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]
Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie +14 more
core +1 more source
Virus entry—an unwilling collaboration by the cell [PDF]
How simple, lifeless particles such as viruses cause devastating diseases and epidemics that affect the everyday lives of most people remain incompletely understood despite intense research efforts. We have determined the genomic sequences of hundreds of viruses, analyzed their structures and composition, and probed their replication mechanisms.
Helenius Ari, Moss Bernard
openaire +4 more sources
Microtubules in Influenza Virus Entry and Egress [PDF]
Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs. It is necessary to understand the detailed and complex interactions between influenza virus and its host cells in order to identify successful strategies for therapeutic intervention.
Caitlin Simpson, Yohei Yamauchi
openaire +5 more sources
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions [PDF]
Hepatitis C virus (HCV) infection is associated with chronic liver disease and currently affects about 3% of the world population. Although much has been learned about the function of individual viral proteins, the role of the HCV p7 protein in virus ...
Ralf Bartenschlager +17 more
core +1 more source
Nectin-2 Acts as a Viral Entry Mediated Molecule That Binds to Human Herpesvirus 6B Glycoprotein B
Human herpesvirus 6B (HHV-6B) is a T-lymphotropic virus and the etiological agent of exanthem subitum. HHV-6B is present in a latent or persistent form after primary infection and is produced in the salivary glands or transmitted to this organ.
Hirohito Ogawa +5 more
doaj +1 more source
As all the enveloped viruses, the entry of influenza viruses includes a number of steps in host cell infection. This chapter summarizes the current knowledge of the entry pathway and the role of the fusion protein of influenza virus, hemagglutinin, in this process.
openaire +2 more sources
SnapShot: Enveloped Virus Entry
In order to initiate successful infection, viruses have to transmit and deliver their genome from one host cell or organism to another. To achieve this, enveloped viruses must first fuse their membrane with those of the target host cell. Here, we describe the sequence of events leading to the entry of representative enveloped viruses, highlighting the ...
Mercer, Jason +3 more
openaire +2 more sources
Zika virus: mapping and reprogramming the entry [PDF]
The flaviviridae family comprises single-stranded RNA viruses that enter cells via clathrin-mediated pH-dependent endocytosis. Although the initial events of the virus entry have been already identified, data regarding intracellular virus trafficking and delivery to the replication site are limited.
Katarzyna Owczarek +5 more
openaire +4 more sources
Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]
The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J. +5 more
core +1 more source
Analysis of poxvirus host cell entry by electron microscopy [PDF]
Vaccinia virus (VACV) is the prototypic poxvirus and is complex in both composition and life cycle. In contrast to most viruses, poxviruses produce two types of infectious particles with different roles in virus dissemination: Mature virions (MVs ...
Bleck, Christopher Karl Ernst
core +1 more source

