Results 11 to 20 of about 2,750,709 (301)
, 2013 Hepatitis C virus (HCV) is a hepatotropic virus and a major cause of chronic hepatitis and liver disease worldwide. Initial interactions between HCV virions and hepatocytes are required for productive viral infection and initiation of the viral life cycle.
Zeisel, Mirjam +2 more
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Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. [PDF]
PLoS ONE, 2011 Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Elena Rahn +4 more
doaj +2 more sources
Virus Entry by Endocytosis [PDF]
Advances in Virology, 2013 Advances in Virology ...
Anthony V. Nicola +4 more
doaj +6 more sources
Journal of Cell Science, 2013 The goal of a virus particle is to transport its genome in a replication-competent form from an infected cell to an uninfected cell. To enter a new host cell, the majority of viruses take advantage of the endocytic mechanisms of the cell and wait until reaching endocytic vacuoles or ...
Yamauchi, Yohei, Helenius, Ari
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Amino Acids, 2009 Viruses, despite being relatively simple in structure and composition, have evolved to exploit complex cellular processes for their replication in the host cell. After binding to their specific receptor on the cell surface, viruses (or viral genomes) have to enter cells to initiate a productive infection.
Kalia, Manjula, Jameel, Shahid
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Annual Review of Biochemistry, 2010 Although viruses are simple in structure and composition, their interactions with host cells are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular processes that involve hundreds of cellular proteins. Although some viruses have the capacity to penetrate into the cytosol directly through the plasma membrane, most depend
Mercer J, Schelhaas M, Helenius A.
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Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. [PDF]
, 2010 Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Roy, Polly +5 more
core +1 more source
Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]
, 2010 Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm +25 more
core +2 more sources
Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]
, 2015 Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
Temperton, Nigel J. +24 more
core +1 more source
Microbiology Spectrum, 2023 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the Coronavirus disease-19 (COVID-19) pandemic, utilizes angiotensin-converting enzyme 2 (ACE2) as a receptor for virus infection.
Ivonne Melano +8 more
doaj +1 more source