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Hepatitis E virus (HEV) infection is a major cause of acute hepatitis worldwide. It is transmitted enterically but replicates in the liver. Recent studies indicate that HEV exists in two forms: naked, nonenveloped virions that are shed into feces to ...
Xin Yin, Zongdi Feng
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The goal of a virus particle is to transport its genome in a replication-competent form from an infected cell to an uninfected cell. To enter a new host cell, the majority of viruses take advantage of the endocytic mechanisms of the cell and wait until ...
Helenius, Ari, Yamauchi, Yohei
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Virus Entry by Endocytosis [PDF]
Advances in Virology ...
Anthony V. Nicola +4 more
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Viruses, despite being relatively simple in structure and composition, have evolved to exploit complex cellular processes for their replication in the host cell. After binding to their specific receptor on the cell surface, viruses (or viral genomes) have to enter cells to initiate a productive infection.
Kalia, Manjula, Jameel, Shahid
openaire +2 more sources
Virus Entry: Open Sesame [PDF]
Detailed information about the replication cycle of viruses and their interactions with host organisms is required to develop strategies to stop them. Cell biology studies, live-cell imaging, and systems biology have started to illuminate the multiple and subtly different pathways that animal viruses use to enter host cells.
Marsh, Mark, Helenius, Ari
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Multiple effects of silymarin on the hepatitis C virus lifecycle [PDF]
Silymarin, an extract from milk thistle (Silybum marianum), and its purified flavonolignans have been recently shown to inhibit hepatitis C virus (HCV) infection, both in vitro and in vivo.
Bourne, Nigel +16 more
core +1 more source
Assessing the impact of climate change on vector-borne viruses in the EU through the elicitation of expert opinion [PDF]
Expert opinion was elicited to undertake a qualitative risk assessment to estimate the current and future risks to the European Union (EU) from five vector-borne viruses listed by the World Organization for Animal Health.
Brouwer, A. +7 more
core +1 more source
Entry properties and entry inhibitors of a human H7N9 influenza virus. [PDF]
The recently identified human infections with a novel avian influenza H7N9 virus in China raise important questions regarding possible risk to humans. However, the entry properties and tropism of this H7N9 virus were poorly understood.
Youhui Si +10 more
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Acid dependent infection of Hela and Vero cells by BTV-10 occurs from within early-endosomes following virus uptake by clathrin-mediated endocytosis (Forzan et al., 2007: J Virol 81: 4819-4827).
Sarah Gold +3 more
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Single virus tracking of Ebola virus entry through lipid rafts in living host cells
Ebola virus (EBOV) is one of the most pathogenic viruses in humans which can cause a lethal hemorrhagic fever. Understanding the cellular entry mechanisms of EBOV can promote the development of new therapeutic strategies to control virus replication and ...
Cong Jin +9 more
doaj +1 more source

