Results 11 to 20 of about 2,656,206 (255)

Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent. [PDF]

PLoS ONE, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Elena Rahn, Philipp Petermann, Mei-Ju Hsu, Frazer J Rixon, Dagmar Knebel-Mörsdorf   +4 more
doaj   +2 more sources

Arming vaccinia virus for pancreatic cancer oncolytic virotherapy [PDF]

, 2011
PhDVaccinia virus is a 250-300nm enveloped DNA virus from the poxvirus family and is used as a vector for oncolytic viral gene therapy. No unique cell surface receptor has been identified for Vaccinia virus and the reasons for its tropism for cancer ...
Hiley, Crispin
core   +4 more sources

Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]

, 2015
Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
Temperton, Nigel J., Molesti, E, Barclay, W., Barclay, W, Wendy Barclay (686216), Eleonora Molesti, Nigel Temperton (5830610), Temperton, N, Barclay, Wendy, Edward Wright, Long, J., Molesti, E., Edward Wright (4468198), Molesti, Eleonora, Temperton, N., Long, Jason, Wright, E, Jason Long (40805), Wendy Barclay, Eleonora Molesti (686215), Wright, Edward, Wright, E., Nigel Temperton, Long, J, Jason Long   +24 more
core   +1 more source

Adaptation of hepatitis C virus to mouse CD81 permits infection of mouse cells in the absence of human entry factors [PDF]

, 2010
Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined.
Christiane Brohm, Kathrin Hueging, Michael Ott, Hueging, Kathrin, Brohm, Christiane, Ott, Michael, Bitzegeio, Julia, Dorothea Bankwitz, Herrmann, Eva, Sibylle Haid, Thomas Pietschmann, Mirjam B. Zeisel, Baumert, Thomas F, Iken, Marcus, Haid, Sibylle, Marcus Iken, Julia Bitzegeio, Thomas F. Baumert, Zeisel, Mirjam B, Thomas F Baumert, Mirjam B Zeisel, Eva Herrmann, Baumert, Thomas, Bankwitz, Dorothea, Zeisel, Mirjam B., Pietschmann, Thomas   +25 more
core   +2 more sources

A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression

Microbiology Spectrum, 2023
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the Coronavirus disease-19 (COVID-19) pandemic, utilizes angiotensin-converting enzyme 2 (ACE2) as a receptor for virus infection.
Ivonne Melano, Wei-Chung Cheng, Li-Lan Kuo, Yuag-Meng Liu, Yu Chi Chou, Mien-Chie Hung, Michael M. C. Lai, Yuh-Pyng Sher, Wen-Chi Su   +8 more
doaj   +1 more source

Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. [PDF]

, 2010
Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy, Bhattacharya, Roy   +5 more
core   +1 more source

Viral entry and escape from antibody-mediated neutralization influence hepatitis C virus reinfection in liver transplantation [PDF]

, 2010
End-stage liver disease caused by chronic hepatitis C virus (HCV) infection is a leading cause for liver transplantation (LT). Due to viral evasion from host immune responses and the absence of preventive antiviral strategies, reinfection of the graft is
Pessaux, Patrick, Doffoel, Michel, Leroux-Roels, G., Stoll-Keller, Françoise, Michel Doffoël, Patel, Arvind H, Samira Fafi-Kremer, Fofana, I., Soulier, E., Patric Carolla, Fafi-Kremer, S., Doffoel, M., Stoll-Keller, F., Cosset, F.-L., Meuleman, Philip, Fafi-Kremer, Samira, Eric Soulier, Philip Meuleman, Isabel Fofana, Wolf, P., Soulier, Eric, Cosset, François-Loic, François-Loïc Cosset, Leroux-Roels, Geert, Wolf, Philippe, Françoise Stoll-Keller, Philippe Wolf, Carolla, Patric, Pessaux, P., Meuleman, P., Baumert, Thomas F, Patel, A.H., Fofana, Isabel, Patrick Pessaux, Thomas F. Baumert, Arvind H. Patel, Geert Leroux-Roels, Carolla, P., Baumert, T.F.   +38 more
core   +1 more source

A clathrin independent macropinocytosis-like entry mechanism used by bluetongue virus-1 during infection of BHK cells.

PLoS ONE, 2010
Acid dependent infection of Hela and Vero cells by BTV-10 occurs from within early-endosomes following virus uptake by clathrin-mediated endocytosis (Forzan et al., 2007: J Virol 81: 4819-4827).
Sarah Gold, Paul Monaghan, Peter Mertens, Terry Jackson   +3 more
doaj   +1 more source

Entry properties and entry inhibitors of a human H7N9 influenza virus. [PDF]

PLoS ONE, 2014
The recently identified human infections with a novel avian influenza H7N9 virus in China raise important questions regarding possible risk to humans. However, the entry properties and tropism of this H7N9 virus were poorly understood.
Youhui Si, Jianguo Li, Yuqiang Niu, Xiuying Liu, Lili Ren, Li Guo, Min Cheng, Hongli Zhou, Jianwei Wang, Qi Jin, Wei Yang   +10 more
doaj   +1 more source

Single virus tracking of Ebola virus entry through lipid rafts in living host cells

Biosafety and Health, 2020
Ebola virus (EBOV) is one of the most pathogenic viruses in humans which can cause a lethal hemorrhagic fever. Understanding the cellular entry mechanisms of EBOV can promote the development of new therapeutic strategies to control virus replication and ...
Cong Jin, Bin Che, Zhengyuan Guo, Chuan Li, Yang Liu, Wei Wu, Shiwen Wang, Dexin Li, Zongqiang Cui, Mifang Liang   +9 more
doaj   +1 more source