Results 41 to 50 of about 2,979,740 (254)

HIV‐1 matrix domain removal ameliorates virus assembly and processing defects incurred by positive nucleocapsid charge elimination

FEBS Open Bio, 2015
Human immunodeficiency virus type 1 nucleocapsid (NC) basic residues presumably contribute to virus assembly via RNA, which serves as a scaffold for Gag–Gag interaction during particle assembly.
Li-Jung Ko, Fu-Hsien Yu, Kuo-Jung Huang, Chin-Tien Wang   +3 more
doaj   +1 more source

The Revisited Genome of Bacillus subtilis Bacteriophage SPP1

Viruses, 2018
Bacillus subtilis bacteriophage SPP1 is a lytic siphovirus first described 50 years ago. Its complete DNA sequence was reported in 1997. Here we present an updated annotation of the 44,016 bp SPP1 genome and its correlation to different steps of the ...
Lia M. Godinho, Mehdi El Sadek Fadel, Céline Monniot, Lina Jakutyte, Isabelle Auzat, Audrey Labarde, Karima Djacem, Leonor Oliveira, Rut Carballido-Lopez, Silvia Ayora, Paulo Tavares   +10 more
doaj   +1 more source

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]

, 2013
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray, Paramasivam, S, Kotecha, A, Wilsden, G, Parida, Satya, Paton, David, Ren, Junyuan, Al-Khalil, Tara, Lomonossoff, GP, Li, Yanmin, Belsham, GJ, Loureiro, S, Kotecha, Abhay, Belsham, Graham, Owens, R, Stuart, David I, Lomonossoff, George P., Porta, C, Xu, X, Parida, S, Lomonossoff, George P, Burman, Alison, Paton, D, Jones, IM, Curry, S, Blesham, Graham J., Paramasivam, Saravanan, Xu, Xiaodong, Stuart, DI, Charleston, Bryan, Jackson, T, Charleston, B, Burman, A, Jones, Ian M., Porta, Claudine, Ren, J, Stuart, David I., Fry, E, Jones, Ian M, Ferris, N, Ferris, Nigel, Loureiro, Silvia, Belsham, Graham J, Curry, Stephen, Jackson, Terry, Al-Khalil, T, Li, Y, Fry, Elizabeth, Wilsden, Ginette   +48 more
core   +1 more source

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]

, 2013
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy   +3 more
core   +1 more source

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F., Palmarini, M., Ratinier Maxime, Ratinier, Maxime, Golder, Matthew, Nunes, S.F., Alessia Armezzani, Sandro Filipe Nunes, Kathryn Allan, Allan Kathryn, Allan, K., Rixon, Frazer, Golder, M., Allan, Kathryn, Nunes Sandro Filipe, Frazer Rixon, Bayoumy, Amr, Shaw, A., Matthew Golder, Franzoni, G., Caporale Marco, Giulia Franzoni, Golder Matthew, Nunes, Sandro Filipe, Bayoumy Amr, Shaw, Andrew, Amr Bayoumy, Palmarini Massimo, Armezzani, A., Shaw Andrew, Palmarini, Massimo, Ratinier, M., Armezzani, Alessia, Franzoni Giulia, Franzoni, Giulia, Maxime Ratinier, Andrew Shaw, Rixon Frazer, Marco Caporale, Massimo Palmarini, Armezzani Alessia, Bayoumy, A., Caporale, Marco, Caporale, M.   +43 more
core   +1 more source

Cleavage and Structural Transitions during Maturation of Staphylococcus aureus Bacteriophage 80α and SaPI1 Capsids

Viruses, 2017
In the tailed bacteriophages, DNA is packaged into spherical procapsids, leading to expansion into angular, thin-walled mature capsids. In many cases, this maturation is accompanied by cleavage of the major capsid protein (CP) and other capsid-associated
James L. Kizziah, Keith A. Manning, Altaira D. Dearborn, Erin A. Wall, Laura Klenow, Rosanne L. L. Hill, Michael S. Spilman, Scott M. Stagg, Gail E. Christie, Terje Dokland   +9 more
doaj   +1 more source

Role of Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly

Frontiers in Immunology, 2018
Hepatitis C virus (HCV) glycoproteins E1 and E2 form a heterodimer to constitute viral envelope proteins, which play an essential role in virus entry. E1 does not directly interact with host receptors, and its functions in viral entry are exerted mostly ...
Yimin Tong, Dimitri Lavillette, Dimitri Lavillette, Qingchao Li, Qingchao Li, Jin Zhong, Jin Zhong   +6 more
doaj   +1 more source

CryoEM of Viral Ribonucleoproteins and Nucleocapsids of Single-Stranded RNA Viruses

Viruses, 2023
Single-stranded RNA viruses (ssRNAv) are characterized by their biological diversity and great adaptability to different hosts; traits which make them a major threat to human health due to their potential to cause zoonotic outbreaks.
Andrea Modrego, Diego Carlero, Rocío Arranz, Jaime Martín-Benito   +3 more
doaj   +1 more source

ASFV pE146L-induced ER remodeling is essential for viral replication

Journal of Virology
African swine fever virus (ASFV) causes a severe hemorrhagic disease, posing a significant threat to the global pig industry. Although the ASFV encodes nearly 200 proteins, the functions of many remain unknown.
Yilin Guo, Sai Niu, Xueying Wang, Zixuan Wang, Rui Liang, Yubei Tan, Zhen Fu, Zhelin Su, Juan Xu, Hongjun Chen, Yuejun Shi, Limeng Sun, Guiqing Peng   +12 more
doaj   +1 more source

Physical Virology in Spain

Biophysica, 2023
Virus particles consist of a protein coat that protects their genetic material and delivers it to the host cell for self-replication. Understanding the interplay between virus structure and function is a requirement for understanding critical processes ...
David Reguera, Pedro J. de Pablo, Nicola G. A. Abrescia, Mauricio G. Mateu, Javier Hernández-Rojas, José R. Castón, Carmen San Martín   +6 more
doaj   +1 more source