Results 31 to 40 of about 71,588 (336)
Norovirus MLKL-like protein initiates cell death to induce viral egress
Nature, 2023 Non-enveloped viruses require cell lysis to release new virions from infected cells, suggesting that these viruses require mechanisms to induce cell death.
Guo-Xun Wang +4 more
semanticscholar +1 more source
mBio, 2023 Members of the Apicomplexa phylum possess specialized secretory organelles that discharge, apically and in a timely regulated manner, key factors implicated in parasite motility, host cell invasion, egress and subversion of host cellular functions.
David J. Dubois +7 more
doaj +1 more source
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress
Developmental Cell, 2021 Viral entry and egress are important determinants of virus infectivity and pathogenicity. β-coronaviruses, including the COVID-19 virus SARS-CoV-2 and mouse hepatitis virus (MHV), exploit the lysosomal exocytosis pathway for egress.
Di Chen +6 more
semanticscholar +1 more source
Hepatitis B virus hijacks TSG101 to facilitate egress via multiple vesicle bodies
PLoS Pathogens, 2023 Hepatitis B virus (HBV) chronically infects 296 million individuals and there is no cure. As an important step of viral life cycle, the mechanisms of HBV egress remain poorly elucidated. With proteomic approach to identify capsid protein (HBc) associated
Yingcheng Zheng +15 more
semanticscholar +1 more source
Journal of Virology, 2023 BmNPV is a severe pathogen that infects mainly Bombyx mori, a domesticated insect of economic importance, and accounts for approximately 15% of economic losses in sericulture. BV production plays a key role in systemic BmNPV infection of larvae. ABSTRACT
Congyue Yao +7 more
semanticscholar +1 more source
mBio, 2022 Toxoplasma gondii is an intracellular apicomplexan parasite that relies on cyclic GMP (cGMP)-dependent signaling to trigger timely egress from host cells in response to extrinsic and intrinsic signals.
Shu Ye +2 more
doaj +1 more source
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
Nature Communications, 2021 Since the outbreak of the SARS-CoV-2 pandemic, there have been intense structural studies on purified viral components and inactivated viruses. However, structural and ultrastructural evidence on how the SARS-CoV-2 infection progresses in the native ...
L. Mendonça +19 more
semanticscholar +1 more source
eLife, 2021 Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is
Nicholas Rinkenberger +5 more
doaj +1 more source
A malaria parasite phospholipase facilitates efficient asexual blood stage egress. [PDF]
, 2023 Malaria parasite release (egress) from host red blood cells involves parasite-mediated membrane poration and rupture, thought to involve membrane-lytic effector molecules such as perforin-like proteins and/or phospholipases.
Calvani, Enrica +21 more
core +3 more sources
Evaluation on Egress Safety of Nursing Hospital Considering the Smoke Exhaust System
Fire, 2022 This study aimed to evaluate the egress safety in nursing hospitals based on the capacity of the smoke exhaust system. To this end, the available safe egress time was calculated by analyzing changes in visibility, carbon monoxide, carbon dioxide, oxygen ...
Seung-Ho Choi +3 more
doaj +1 more source