Results 31 to 40 of about 48,176 (297)

The host exosome pathway underpins biogenesis of the human cytomegalovirus virion

eLife, 2020
Human Cytomegalovirus (HCMV) infects over half the world's population, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals.
Declan L Turner, Denis V Korneev, John G Purdy, Alex de Marco, Rommel A Mathias   +4 more
doaj   +1 more source

Myosin-9 is required for lysosome-mediated nonlytic reovirus egress. [PDF]

PLoS Pathog
Mammalian orthoreoviruses (reoviruses) are nonenveloped, double-stranded RNA viruses that assemble progeny particles in cytoplasmic viral factories (VFs) and exit some types of cells using a nonlytic release mechanism.
Fernández de Castro I, Sachse M, Taylor GM, Fernández JJ, Tenorio R, Fernández-Sánchez SY, Dermody TS, Risco C.   +7 more
europepmc   +2 more sources

Herpesvirus Assembly and Egress [PDF]

Journal of Virology, 2002
Herpesvirus particles consist of four morphologically distinct structures, the core, capsid, tegument, and envelope. The inner nucleoprotein core comprising the linear double-stranded DNA genome is included in an icosahedral (T=16) capsid shell of 150 hexons and 12 pentons.
openaire   +2 more sources

iTRAQ-Based Phosphoproteomic Analysis of Toxoplasma gondii Tachyzoites Provides Insight Into the Role of Phosphorylation for its Invasion and Egress

Frontiers in Cellular and Infection Microbiology, 2020
The invasion and egress are two key steps in lytic cycle vital to the propagation of Toxoplasma gondii infection, and phosphorylation is believed to play important roles in these processes. However, the phosphoproteome of T.
Cheng He, Mei-zhen Xu, Shuai Pan, Hui Wang, Hong-juan Peng, Zhuan-zhuan Liu   +5 more
doaj   +1 more source

Scalable context-dependent analysis of emergency egress models [PDF]

, 2012
Pervasive environments offer an increasing number of services to a large number of people moving within these environments, including timely information about where to go and when, and contextual information about the surrounding environment.
Harrison, Michael D, D. Latella, Hillston, Jane, Massink, Mieke, Latella, Diego, Bracciali, Andrea, M. Massink, A. Bracciali, M. D. Harrison, J. Hillston   +9 more
core   +1 more source

Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum

mBio, 2018
The human malaria parasite Plasmodium falciparum requires efficient egress out of an infected red blood cell for pathogenesis. This egress event is highly coordinated and is mediated by several signaling proteins, including the plant-like P.
Sabrina Absalon, Karin Blomqvist, Rachel M. Rudlaff, Travis J. DeLano, Michael P. Pollastri, Jeffrey D. Dvorin   +5 more
doaj   +1 more source

Epstein-Barr Virus Exploits the Secretory Pathway to Release Virions

Microorganisms, 2020
Herpesvirus egress mechanisms are strongly associated with intracellular compartment remodeling processes. Previously, we and other groups have described that intracellular compartments derived from the Golgi apparatus are the maturation sites of Epstein-
Asuka Nanbo
doaj   +1 more source

Lessons from the evacuation of the World Trade Center, Sept 11th 2001 for the future development of computer simulations [PDF]

, 2005
This paper provides an overview of the state of the art in evacuation simulations. These interactive computer based tools have been developed to help the owners and designers of large public buildings to assess the risks that occupants might face during ...
C.W. Johnson, Johnson, C.W.
core   +1 more source

Evacuation Solutions for Individuals with Functional Limitations in the Indoor Built Environment: A Scoping Review

Buildings, 2023
The built environment continues to become increasingly accessible to people with disabilities, yet there remains a lack of focus on how these individuals are evacuated in emergencies.
Abdulrahman Al Bochi, Brad W. R. Roberts, Waqas Sajid, Zeyad Ghulam, Mark Weiler, Yashoda Sharma, Cesar Marquez-Chin, Steven Pong, Albert H. Vette, Tilak Dutta   +9 more
doaj   +1 more source

Egress of Alphaherpesviruses [PDF]

Journal of Virology, 2006
In their recent papers on the assembly of alphaherpesviruses, Wild et al. ([13][1]) and Leuzinger et al. ([3][2]) propose that the egress of herpesvirus capsids from the nucleus and formation of the enveloped herpesvirus virion occur by two alternative routes.
Thomas C. Mettenleiter, Tony Minson
openaire   +1 more source