Results 31 to 40 of about 48,237 (296)

A malaria parasite phospholipase facilitates efficient asexual blood stage egress. [PDF]

open access: yes, 2023
Malaria parasite release (egress) from host red blood cells involves parasite-mediated membrane poration and rupture, thought to involve membrane-lytic effector molecules such as perforin-like proteins and/or phospholipases.
Konstantinos Koussis (710704)   +10 more
core   +6 more sources

A Signaling Factor Linked to Toxoplasma gondii Guanylate Cyclase Complex Controls Invasion and Egress during Acute and Chronic Infection

open access: yesmBio, 2022
Toxoplasma gondii is an intracellular apicomplexan parasite that relies on cyclic GMP (cGMP)-dependent signaling to trigger timely egress from host cells in response to extrinsic and intrinsic signals.
Shu Ye   +2 more
doaj   +1 more source

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection

open access: yeseLife, 2021
Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is
Nicholas Rinkenberger   +5 more
doaj   +1 more source

The Egress Enabler: Development and psychometric evaluation of an instrument to measure egressibility

open access: yesDisability and Health Journal, 2023
Egressibility has been defined as a person-environment fit issue and describes accessibility to means of evacuation. Although egressibility concerns everyone, it has become a useful concept particularly in relation to safety and accessibility for people with functional limitations, commonly highlighted as a vulnerable group in egress scenarios ...
Erik Smedberg   +5 more
openaire   +2 more sources

Eviction notice served on Toxoplasma

open access: yeseLife, 2022
The gene RARRES3 uses an unexpected strategy to eliminate the parasite Toxoplasma gondii from human cells.
Juan C Sánchez-Arcila, Kirk DC Jensen
doaj   +1 more source

Egress from a settlement school: where are the children of Rural Education?

open access: yesRevista Brasileira de Educação do Campo, 2019
The text - and the research that originated it - starts from an apparently simple question: Where are the children of Rural Education? Where do our pedagogical, political and social efforts go when we devote ourselves to an education in the countryside ...
Rosimar Serena Siqueira Esquinsani   +2 more
doaj   +1 more source

The Dually Localized EF-Hand Domain-Containing Protein TgEFP1 Regulates the Lytic Cycle of Toxoplasma gondii

open access: yesCells, 2022
The propagation of the obligate intracellular parasite Toxoplasma gondii is tightly regulated by calcium signaling. However, the mechanisms by which calcium homeostasis and fluxes are regulated in this human pathogen are not fully understood. To identify
Noopur Dave   +2 more
doaj   +1 more source

Malarial proteases and host cell egress: an 'emerging' cascade. [PDF]

open access: yes, 2008
Malaria is a scourge of large swathes of the globe, stressing the need for a continuing effort to better understand the biology of its aetiological agent. Like all pathogens of the phylum Apicomplexa, the malaria parasite spends part of its life inside a
Blackman, Michael J
core   +1 more source

An Extracellular Redox Signal Triggers Calcium Release and Impacts the Asexual Development of Toxoplasma gondii

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The ability of an organism to sense and respond to environmental redox fluctuations relies on a signaling network that is incompletely understood in apicomplexan parasites such as Toxoplasma gondii.
Eduardo Alves   +8 more
doaj   +1 more source

Nuclear Egress

open access: yes, 2020
During viral replication, herpesviruses utilize a unique strategy, termed nuclear egress, to translocate capsids from the nucleus into the cytoplasm. This initial budding step transfers a newly formed capsid from within the nucleus, too large to fit through nuclear pores, through the inner nuclear membrane to the perinuclear space.
Elizabeth B, Draganova   +2 more
openaire   +2 more sources

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