Results 41 to 50 of about 48,237 (296)

The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress

mBio, 2018
Apicomplexa are obligate intracellular parasites that actively invade, replicate within, and egress from host cells. The parasite actinomyosin-based molecular motor complex (often referred to as the glideosome) is considered an important mediator of ...
Abigail J. Perrin, Christine R. Collins, Matthew R. G. Russell, Lucy M. Collinson, David A. Baker, Michael J. Blackman   +5 more
doaj   +1 more source

Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites [PDF]

, 2014
This work was funded by grants from the Wellcome Trust (WT098051 and 079643/Z/06/Z) and the Medical Research Council (G0501670) to OB, a Wellcome Trust project grant to DB (WT094752), a Wellcome Trust Grant (WT093228) to TKS, a Marie Curie Fellowship ...
Katrin Volkmann, Chappell, Lia, Brochet, M., Oliver Billker, Eloise Thompson, Billker, Oliver,, Mathieu Brochet, Berriman, Matthew, Jyoti Choudhary (261900), Frank Schwach, Rayner, Julian C., Rayner, Julian C, Jyoti Choudhary, Lia Chappell (530631), Sebastian, Sarah, Lia Chappell, Chappell, L., Terry K. Smith (112550), Gomes, Ana Rita, Frank Schwach (530630), Ana Rita Gomes, Oliver Billker (92636), Smith, T.K., Thompson, E., Schwach, F., Sebastian, S., Baker, David A, Volkmann, K., Sarah Sebastian (530629), Volkmann, Katrin, David A Baker, Terry K Smith, Ana Rita Gomes (220735), Collins, Mark O., Smith, Terry K., Mark O Collins, Gomes, A.R., Collins, M.O., David A. Baker (122252), Choudhary, J., Julian C Rayner, Brochet, Mathieu, Mathieu Brochet (149272), Billker, Oliver, Collins, Mark O, Mark O. Collins (131229), Billker, O., Schwach, Frank, Berriman, M., Sarah Sebastian, Rayner, J.C., Matthew Berriman (5353), Baker, David A., Thompson, Eloise, Smith, Terry K, Matthew Berriman, Choudhary, Jyoti, Eloise Thompson (376344), Baker, D.A., Julian C. Rayner (121198), Katrin Volkmann (149256)   +60 more
core   +1 more source

The host exosome pathway underpins biogenesis of the human cytomegalovirus virion

eLife, 2020
Human Cytomegalovirus (HCMV) infects over half the world's population, is a leading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals.
Declan L Turner, Denis V Korneev, John G Purdy, Alex de Marco, Rommel A Mathias   +4 more
doaj   +1 more source

Egress of Alphaherpesviruses [PDF]

Journal of Virology, 2006
In their recent papers on the assembly of alphaherpesviruses, Wild et al. ([13][1]) and Leuzinger et al. ([3][2]) propose that the egress of herpesvirus capsids from the nucleus and formation of the enveloped herpesvirus virion occur by two alternative routes.
Thomas C. Mettenleiter, Tony Minson
openaire   +1 more source

Herpesvirus Assembly and Egress [PDF]

Journal of Virology, 2002
Herpesvirus particles consist of four morphologically distinct structures, the core, capsid, tegument, and envelope. The inner nucleoprotein core comprising the linear double-stranded DNA genome is included in an icosahedral (T=16) capsid shell of 150 hexons and 12 pentons.
openaire   +2 more sources

Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum

mBio, 2018
The human malaria parasite Plasmodium falciparum requires efficient egress out of an infected red blood cell for pathogenesis. This egress event is highly coordinated and is mediated by several signaling proteins, including the plant-like P.
Sabrina Absalon, Karin Blomqvist, Rachel M. Rudlaff, Travis J. DeLano, Michael P. Pollastri, Jeffrey D. Dvorin   +5 more
doaj   +1 more source

iTRAQ-Based Phosphoproteomic Analysis of Toxoplasma gondii Tachyzoites Provides Insight Into the Role of Phosphorylation for its Invasion and Egress

Frontiers in Cellular and Infection Microbiology, 2020
The invasion and egress are two key steps in lytic cycle vital to the propagation of Toxoplasma gondii infection, and phosphorylation is believed to play important roles in these processes. However, the phosphoproteome of T.
Cheng He, Mei-zhen Xu, Shuai Pan, Hui Wang, Hong-juan Peng, Zhuan-zhuan Liu   +5 more
doaj   +1 more source

Scalable context-dependent analysis of emergency egress models [PDF]

, 2012
Pervasive environments offer an increasing number of services to a large number of people moving within these environments, including timely information about where to go and when, and contextual information about the surrounding environment.
Harrison, Michael D, D. Latella, Hillston, Jane, Massink, Mieke, Latella, Diego, Bracciali, Andrea, M. Massink, A. Bracciali, M. D. Harrison, J. Hillston   +9 more
core   +1 more source

Epstein-Barr Virus Exploits the Secretory Pathway to Release Virions

Microorganisms, 2020
Herpesvirus egress mechanisms are strongly associated with intracellular compartment remodeling processes. Previously, we and other groups have described that intracellular compartments derived from the Golgi apparatus are the maturation sites of Epstein-
Asuka Nanbo
doaj   +1 more source

Evacuation Solutions for Individuals with Functional Limitations in the Indoor Built Environment: A Scoping Review

Buildings, 2023
The built environment continues to become increasingly accessible to people with disabilities, yet there remains a lack of focus on how these individuals are evacuated in emergencies.
Abdulrahman Al Bochi, Brad W. R. Roberts, Waqas Sajid, Zeyad Ghulam, Mark Weiler, Yashoda Sharma, Cesar Marquez-Chin, Steven Pong, Albert H. Vette, Tilak Dutta   +9 more
doaj   +1 more source