Results 51 to 60 of about 48,237 (296)
Lessons from the evacuation of the World Trade Center, Sept 11th 2001 for the future development of computer simulations [PDF]
, 2005 This paper provides an overview of the state of the art in evacuation simulations. These interactive computer based tools have been developed to help the owners and designers of large public buildings to assess the risks that occupants might face during ...
C.W. Johnson, Johnson, C.W.
core +1 more source
Nuclear entry and egress of parvoviruses
Molecular Microbiology, 2022 AbstractParvoviruses are small non‐enveloped single‐stranded DNA viruses, which depend on host cell nuclear transcriptional and replication machinery. After endosomal exposure of nuclear localization sequence and a phospholipase A2 domain on the capsid surface, and escape into the cytosol, parvovirus capsids enter the nucleus.
Mattola, Salla +5 more
openaire +3 more sources
Mechanisms of bunyavirus morphogenesis and egress
Journal of General Virology, 2023 Unlike many segmented negative-sense RNA viruses, most members of the Bunyavirales bud at Golgi membranes, as opposed to the plasma membrane. Central players in this assembly process are the envelope glycoproteins, Gn and Gc, which upon translation undergo proteolytic processing, glycosylation and trafficking to the Golgi, where they interact with ...
Jake Barker +2 more
openaire +3 more sources
Frontiers in Immunology, 2017 Regulatory T cells (Tregs) restrict overexuberant lymphocyte activation. While close proximity between Tregs and their suppression targets is important for optimal inhibition, and literature indicates that draining lymph nodes (LNs) may serve as a prime ...
Shuang Geng +10 more
doaj +1 more source
Brucella Egresses from Host Cells Exploiting Multivesicular Bodies
mBio, 2023 Host cell egress is a critical step in the life cycle of intracellular pathogens, especially in microbes capable of establishing chronic infections. The Gram-negative bacterium Brucella belongs to such a group of pathogens. Even though much has been done
Juan Manuel Spera +3 more
doaj +1 more source
Viruses, 2019 Lassa virus (LASV) and Mopeia virus (MOPV) are two closely related, rodent-born mammarenaviruses. LASV is the causative agent of Lassa fever, a deadly hemorrhagic fever endemic in West Africa, whereas MOPV is non-pathogenic in humans.
Nicolas Baillet +9 more
doaj +1 more source
Senior Drivers’ Body Movement Strategies for Getting in and out of Cars: A Study by Vehicle Typology
Vehicles, 2023 During normal ageing, physical changes take place in the biomechanical, musculoskeletal, and psychomotor systems, that reduce strength, flexibility, motor coordination, balance, and precision of movements.
Susana C. F. Fernandes
doaj +1 more source
CAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells
Viruses, 2022 The replication of Ebola virus (EBOV) is dependent upon actin functionality, especially at cell entry through macropinocytosis and at release of virus from cells.
Hiroyuki Mori +7 more
doaj +1 more source
Access and egress times to high-speed rail stations: a spatiotemporal accessibility analysis [PDF]
, 2018 Accessibility by high-speed rail (HSR) depends not only on station-to-station travel time, but also on access and egress times, which can be determining factors in total journey travel time.
Moyano, Amparo +2 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks +5 more
wiley +1 more source