Results 51 to 60 of about 48,176 (297)
Thymic egress: S1P of 1000 [PDF]
F1000 Biology Reports, 2009 Recent studies have begun to illuminate the mechanism of T-cell export from the thymus, with the identification of a required lysophospholipid receptor, two upstream transcription factors, and several downstream regulators of cytoskeleton dynamics. This work has generated immediate translational impact, aiding the design of immunosuppressant drugs and ...
Zachariah, Marcus A, Cyster, Jason G
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
Malaria Journal, 2013 Background Egress of Plasmodium falciparum, from erythrocytes at the end of its asexual cycle and subsequent parasite invasion into new host cells, is responsible for parasite dissemination in the human body.
Glushakova Svetlana +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Emergency egress from elevated workstations [PDF]
"Procedures and equipment are recommended for worker emergency egress from elevated workstations. The standard is designed to assure workers of a means of emergency egress during situations in which there could be a threat to life, health, or safety ...
core +1 more source
Visualizing Nudivirus Assembly and Egress
mBio, 2020 The dynamics of nuclear envelope has a critical role in multiple cellular processes. However, little is known regarding the structural changes occurring inside the nucleus or at the inner and outer nuclear membranes. For viruses assembling inside the nucleus, remodeling of the intranuclear membrane plays an important role in the process of
Sailakshmi Velamoor +7 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
THE FIRST/LAST MILE PROBLEM AS KEY FACTOR IN PASSENGER TRANSPORT MODAL CHOICE
Perner’s ContactsThe first and last mile leg of a journey presents a challenge for the traveller to get to the transportation hub and continue on the main leg of their journey.
Martin Václavík, Ivana Olivková
doaj +1 more source
Epstein–Barr Virus Acquires Its Final Envelope on Intracellular Compartments With Golgi Markers
Frontiers in Microbiology, 2018 Herpesvirus subfamilies typically acquire their final envelope in various cytoplasmic compartments such as the trans-Golgi network (TGN), and endosomes prior to their secretion into the extracellular space. However, the sites for the final envelopment of
Asuka Nanbo, Takeshi Noda, Yusuke Ohba
doaj +1 more source