Results 71 to 80 of about 71,588 (336)

Microtubules in Influenza Virus Entry and Egress

Viruses, 2020
Influenza viruses are respiratory pathogens that represent a significant threat to public health, despite the large-scale implementation of vaccination programs.
Caitlin Simpson, Y. Yamauchi
semanticscholar   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

Nature Communications, 2020
Asexual proliferation of the Plasmodium parasites that cause malaria follows a developmental program that alternates non-canonical intraerythrocytic replication with dissemination to new host cells.
Aditya S. Paul, Alexandra Miliu, João A. Paulo, J. Goldberg, Arianna M. Bonilla, L. Berry, M. Seveno, C. Braun‐Breton, Aziz L. Kosber, Brendan Elsworth, Jose S. N. Arriola, M. Lebrun, S. Gygi, Mauld H. Lamarque, M. Duraisingh   +14 more
semanticscholar   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

Defining Molecular Mechanism of Egress in Cryptosporidium [PDF]

, 2021
Recent studies have identified Cryptosporidium as a major contributor to childhood disease in endemic areas. Current interventions are not ideal where only few have demonstrated anti-cryptosporidial activity and are often associated with relapses in ...
Nava, Samantha
core   +3 more sources

Visualizing Nudivirus Assembly and Egress

mBio, 2020
The dynamics of nuclear envelope has a critical role in multiple cellular processes. However, little is known regarding the structural changes occurring inside the nucleus or at the inner and outer nuclear membranes. For viruses assembling inside the nucleus, remodeling of the intranuclear membrane plays an important role in the process of
Sailakshmi Velamoor, Allan Mitchell, Bruno M. Humbel, WonMo Kim, Charlotte Pushparajan, Gabriel Visnovsky, Laura N. Burga, Mihnea Bostina   +7 more
openaire   +3 more sources

Emergency egress from elevated workstations [PDF]

"Procedures and equipment are recommended for worker emergency egress from elevated workstations. The standard is designed to assure workers of a means of emergency egress during situations in which there could be a threat to life, health, or safety ...

core   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

Cytoplasmic free Ca²⁺ is essential for multiple steps in malaria parasite egress from infected erythrocytes

Malaria Journal, 2013
Background Egress of Plasmodium falciparum, from erythrocytes at the end of its asexual cycle and subsequent parasite invasion into new host cells, is responsible for parasite dissemination in the human body.
Glushakova Svetlana, Lizunov Vladimir, Blank Paul S, Melikov Kamran, Humphrey Glen, Zimmerberg Joshua   +5 more
doaj   +1 more source

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source