Results 81 to 90 of about 71,588 (336)

Structural basis for capsid recruitment and coat formation during HSV-1 nuclear egress

bioRxiv, 2020
During herpesvirus infection, egress of nascent viral capsids from the nucleus is mediated by the viral nuclear egress complex (NEC). NEC deforms the inner nuclear membrane (INM) around the capsid by forming a hexagonal array.
Elizabeth B. Draganova, Jiayan Zhang, Hong Z. Zhou, E. Heldwein   +3 more
semanticscholar   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Epstein–Barr Virus Acquires Its Final Envelope on Intracellular Compartments With Golgi Markers

Frontiers in Microbiology, 2018
Herpesvirus subfamilies typically acquire their final envelope in various cytoplasmic compartments such as the trans-Golgi network (TGN), and endosomes prior to their secretion into the extracellular space. However, the sites for the final envelopment of
Asuka Nanbo, Takeshi Noda, Yusuke Ohba
doaj   +1 more source

Ins and Outs of Reovirus: Vesicular Trafficking in Viral Entry and Egress

Trends in Microbiology, 2020
Cell entry and egress are essential steps in the viral life cycle that govern pathogenesis and spread. Mammalian orthoreoviruses (reoviruses) are nonenveloped viruses implicated in human disease that serve as tractable models for studies of pathogen–host
Alexa N. Roth, Pavithra Aravamudhan, Isabel Fernández de Castro, Raquel Tenorio, C. Risco, T. Dermody   +5 more
semanticscholar   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

High-rise office egress: the human factors

, 2007
This paper summarizes the results of several studies that have assessed the human factors that affect egress from high-rise office towers during emergencies.
Proulx, G.
core   +1 more source

THE FIRST/LAST MILE PROBLEM AS KEY FACTOR IN PASSENGER TRANSPORT MODAL CHOICE

Perner’s Contacts
The first and last mile leg of a journey presents a challenge for the traveller to get to the transportation hub and continue on the main leg of their journey.
Martin Václavík, Ivana Olivková
doaj   +1 more source

Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain

mBio, 2023
Following each round of replication, daughter merozoites of the malaria parasite Plasmodium falciparum escape (egress) from the infected host red blood cell (RBC) by rupturing the parasitophorous vacuole membrane (PVM) and the RBC membrane (RBCM).
Sumit Mukherjee, Armiyaw S. Nasamu, Kelly C. Rubiano, Daniel E. Goldberg   +3 more
doaj   +1 more source

SARS-CoV-2 lysosomal egress pathway

, 2021
The early stages of the SARS-CoV-2 lifecycle have been relatively well-defined. However, knowledge of how newly assembled SARS-CoV-2 particles egress from cells remains limited.
Rosen, Ariel
core  

Referral Practices and Utilisation of Paediatric Oncology Physiotherapy Services in Ghana: A Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Physical rehabilitation is highly recognised in improving the quality of life of cancer survivors through prehabilitation, sequelae management and palliative care, yet its integration into routine care in Ghana has not been characterised, leading to potential gaps in service access.
Dorothy Ekua Adjabu, Philip Junior Nyarko, Precious Madzimbe, Kofi Adesi Kyei, Tawagidu Mohammed, Sandra Banini   +5 more
wiley   +1 more source