Results 81 to 90 of about 48,176 (297)

Adaptive Kinetic Architecture and Collective Behavior: A Dynamic Analysis for Emergency Evacuation

Buildings, 2019
Adaptive kinetic architecture has emerged from a need for innovative designs that adapt to the environment and changing needs of the occupants. Architectural design and modes of egress are critical in an emergency. Flocking describes a certain collective
Angella Johnson, Size Zheng, Aiichiro Nakano, Goetz Schierle, Joon-Ho Choi   +4 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Numerical Investigation of Unsteady Interaction between Rim Seal Flow and Upstream Vane

Xibei Gongye Daxue Xuebao, 2019
To investigate unsteady interaction mechanism between the rim seal flow in turbine stator-rotor cavity and main flow, detailed unsteady numerical simulations of the flow field and unsteady characteristic of the vane were conducted under different rim ...

doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Safe Egress Scenario Detection: From Baseline to Active Events [PDF]

, 2022
Crowd management in public walking spaces has been a topical research theme. In fact, in some spaces such as squares, stations, and commercial areas, there is a strategic need of addressing the uprising challenges to public safety, ensuring an ...
Mocellin P., Rosati G., Bottin M., Vianello C., Maschio G.   +4 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Making Outbound Route Selection Robust to Egress Point Failure [PDF]

, 2005
Offline inter-domain outbound Traffic Engineering (TE) can be formulated as an optimization problem whose objective is to determine primary egress points for traffic exiting a domain.
Mina Amin, Michael Howarth, Ho, KH, Kin-Hon Ho, Amin, M, Pavlou, G, Pavlou, George, Ho, Kin-Hon, Amin, Mina, George Pavlou, Howarth, Michael, Howarth, MP   +11 more
core   +1 more source