Results 61 to 70 of about 71,588 (336)
mBio, 2021 Malaria is a deadly infectious disease. Rationally designed novel therapeutics will be essential for its control and eradication. ABSTRACT Malaria parasites cause disease through repeated cycles of intraerythrocytic proliferation.
Abigail J. Perrin +9 more
semanticscholar +1 more source
Buildings, 2023 The built environment continues to become increasingly accessible to people with disabilities, yet there remains a lack of focus on how these individuals are evacuated in emergencies.
Abdulrahman Al Bochi +9 more
doaj +1 more source
Host and Viral Factors Involved in Nuclear Egress of Herpes Simplex Virus 1
Viruses, 2021 Herpes simplex virus 1 (HSV-1) replicates its genome and packages it into capsids within the nucleus. HSV-1 has evolved a complex mechanism of nuclear egress whereby nascent capsids bud on the inner nuclear membrane to form perinuclear virions that ...
Jun Arii
semanticscholar +1 more source
Herpesvirus Assembly and Egress [PDF]
Journal of Virology, 2002 Herpesvirus particles consist of four morphologically distinct structures, the core, capsid, tegument, and envelope. The inner nucleoprotein core comprising the linear double-stranded DNA genome is included in an icosahedral (T=16) capsid shell of 150 hexons and 12 pentons.
openaire +2 more sources
Scalable context-dependent analysis of emergency egress models [PDF]
, 2012 Pervasive environments offer an increasing number of services to a large number of people moving within these environments, including timely information about where to go and when, and contextual information about the surrounding environment.
Harrison, Michael D +9 more
core +1 more source
HSV-1 Cytoplasmic Envelopment and Egress
International Journal of Molecular Sciences, 2020 Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA replication, capsid assembly, and genome packaging take place in the infected ...
Imran Ahmad, D. Wilson
semanticscholar +1 more source
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
Nature Communications, 2020 Among the various host cellular processes that are hijacked by flaviviruses, few mechanisms have been described with regard to viral egress. Here we investigate how flaviviruses exploit Src family kinases (SFKs) for exit from infected cells.
Ming-Yuan Li +11 more
semanticscholar +1 more source
Nuclear entry and egress of parvoviruses
Molecular Microbiology, 2022 AbstractParvoviruses are small non‐enveloped single‐stranded DNA viruses, which depend on host cell nuclear transcriptional and replication machinery. After endosomal exposure of nuclear localization sequence and a phospholipase A2 domain on the capsid surface, and escape into the cytosol, parvovirus capsids enter the nucleus.
Mattola, Salla +5 more
openaire +3 more sources
Lessons from the evacuation of the World Trade Center, Sept 11th 2001 for the future development of computer simulations [PDF]
, 2005 This paper provides an overview of the state of the art in evacuation simulations. These interactive computer based tools have been developed to help the owners and designers of large public buildings to assess the risks that occupants might face during ...
C.W. Johnson, Johnson, C.W.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source