Results 11 to 20 of about 48,176 (297)

CRISPR/Cas9-Based Knockout of GNAQ Reveals Differences in Host Cell Signaling Necessary for Egress of Apicomplexan Parasites [PDF]

open access: yesmSphere, 2020
Toxoplasma gondii and members of the genus Plasmodium are obligate intracellular parasites that leave their infected host cell upon a tightly controlled process of egress. Intracellular replication of the parasites occurs within a parasitophorous vacuole,
Paul-Christian Burda   +4 more
doaj   +2 more sources

Malaria parasite egress at a glance [PDF]

open access: yesJournal of Cell Science, 2021
ABSTRACT All intracellular pathogens must escape (egress) from the confines of their host cell to disseminate and proliferate. The malaria parasite only replicates in an intracellular vacuole or in a cyst, and must undergo egress at four distinct phases during its complex life cycle, each time disrupting, in a highly regulated manner,
Michele S. Y Tan, Michael J. Blackman
openaire   +4 more sources

Application Modes of Egress Simulation [PDF]

open access: yes, 2009
Egress models are being used more frequently to simulate people movement; i.e. how people enter, use and leave a building. However, little has been written on the different aspects of people movement that can be examined and how these models may achieve this.
Gwynne, Steve, Kuligowski, E.D.
openaire   +3 more sources

Egress Safety for STUDIO Residential Buildings

open access: yesBuildings
In recent years, the number of studio residential buildings has increased significantly in Korea, as well as in many other countries, due to changes in living patterns.
Khaliunaa Darkhanbat   +3 more
doaj   +2 more sources

Archaeal virus entry and egress [PDF]

open access: yesmicroLife
Abstract Archaeal viruses display a high degree of structural and genomic diversity. Few details are known about the mechanisms by which these viruses enter and exit their host cells. Research on archaeal viruses has lately made significant progress due to advances in genetic tools and imaging techniques, such as cryo-electron tomography
Bastiaan P Kuiper   +4 more
openaire   +4 more sources

Viruses and Nuclear Egress [PDF]

open access: yes, 2022
This Special Issue of Viruses focuses on the topic of viruses and nuclear egress. Nuclear egress is a fascinating process by which herpesvirus nucleocapsids make their way from the nuclear interior to the cytoplasm.

core   +2 more sources

Toxoplasma gondii LCAT Primarily Contributes to Tachyzoite Egress

open access: yesmSphere, 2018
Egress is a crucial phase of the Toxoplasma gondii intracellular lytic cycle. This is a process that drives inflammation and is strongly associated with the pathogenesis observed during toxoplasmosis.
Aric J. Schultz, Vern B. Carruthers
doaj   +2 more sources

A malaria parasite phospholipase facilitates efficient asexual blood stage egress. [PDF]

open access: yes, 2023
Malaria parasite release (egress) from host red blood cells involves parasite-mediated membrane poration and rupture, thought to involve membrane-lytic effector molecules such as perforin-like proteins and/or phospholipases.
Konstantinos Koussis (710704)   +10 more
core   +3 more sources

A Signaling Factor Linked to Toxoplasma gondii Guanylate Cyclase Complex Controls Invasion and Egress during Acute and Chronic Infection

open access: yesmBio, 2022
Toxoplasma gondii is an intracellular apicomplexan parasite that relies on cyclic GMP (cGMP)-dependent signaling to trigger timely egress from host cells in response to extrinsic and intrinsic signals.
Shu Ye   +2 more
doaj   +1 more source

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection

open access: yeseLife, 2021
Toxoplasma gondii is an important human pathogen infecting an estimated one in three people worldwide. The cytokine interferon gamma (IFNγ) is induced during infection and is critical for restricting T. gondii growth in human cells. Growth restriction is
Nicholas Rinkenberger   +5 more
doaj   +1 more source

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