Results 11 to 20 of about 71,588 (336)
Egress Safety Criteria for Nursing Hospitals
Buildings, 2022 Nursing hospitals have a high probability of casualties during a fire disaster because they have many patients with impaired mobility. In this study, fire and egress simulations were conducted to evaluate the egress safety of a typical nursing hospital ...
Seung Ho Choi +2 more
exaly +4 more sources
Malaria parasite egress at a glance [PDF]
Journal of Cell Science, 2021 All intracellular pathogens must escape (egress) from the confines of their host cell to disseminate and proliferate. The malaria parasite only replicates in an intracellular vacuole or in a cyst, and must undergo egress at four distinct phases during ...
Michele S. Y. Tan, M. Blackman
semanticscholar +6 more sources
β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Cell, 2020 β-Coronaviruses are a family of positive-strand enveloped RNA viruses that includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is known regarding their cellular entry and replication pathways, but their mode of egress remains ...
Gary Whittaker +2 more
exaly +2 more sources
Current Issues in Molecular Biology, 2020 During viral replication, herpesviruses utilize a unique strategy, termed nuclear egress, to translocate capsids from the nucleus into the cytoplasm.
Elizabeth B. Draganova +2 more
semanticscholar +3 more sources
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2
Cell, 2020 Lysosomal cholesterol egress requires two proteins, NPC1 and NPC2, whose defects are responsible for Niemann-Pick disease type C (NPC). Here, we present systematic structural characterizations that reveal the molecular basis for low-pH-dependent ...
Hongwu Qian, Ximing Du, Hongyuan Yang
exaly +2 more sources
Parasite, 2021 Egress plays a vital role in the life cycle of apicomplexan parasites including Eimeria tenella, which has been attracting attention from various research groups.
Yan Xinlei +3 more
doaj +2 more sources
Pedestrian lane formation and its influence on egress efficiency in the presence of an obstacle
Safety Science, 2021 Due to the inevitability of placing obstacles when designing walking facilities, it is important to understand the influence of the obstacle during pedestrian egress to build a safer and more efficient walking environment.
Daichi Yanagisawa +2 more
exaly +2 more sources
The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress
MBio, 2018 Apicomplexa are obligate intracellular parasites that actively invade, replicate within, and egress from host cells. The parasite actinomyosin-based molecular motor complex (often referred to as the glideosome) is considered an important mediator of ...
Christine Collins +2 more
exaly +3 more sources
Revisiting cysteine protease function in Trypanosoma cruzi: implications for parasite egress and differentiation [PDF]
Microbiology SpectrumChagas disease is a major global health concern affecting millions of people worldwide, with limited therapeutic options in its chronic phase and no prophylactic vaccine.
Sara De Grandis +3 more
doaj +2 more sources
Egress of non-enveloped enteric RNA viruses [PDF]
Journal of General Virology, 2021 A long-standing paradigm in virology was that non-enveloped viruses induce cell lysis to release progeny virions. However, emerging evidence indicates that some non-enveloped viruses exit cells without inducing cell lysis, while others engage both lytic ...
I. Owusu +3 more
semanticscholar +2 more sources