ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Synergistic effect of particle packing method, aggregate saturation levels, and paste content in improving the performance of high volume fine recycled aggregate concrete. [PDF]
Khanapur NV +3 more
europepmc +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Chloride-Induced Corrosion Performance of ASR-Contaminated Concrete: Coupled Analysis Using Resistance Variation and NT Build 492 Method. [PDF]
Shi T, Nejadi S, Far H.
europepmc +1 more source
To investigate the reasons for moisture ingress in ready to drink mixes
Rahul N. Eklahare
openalex +1 more source
Modeling moisture ingress in PV modules with different encapsulant and backsheet materials
Youri Blom +7 more
openalex +1 more source
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
Optimization of Cryogenic Gas Separation Systems Based on Exergetic Analysis-The Claude-Heylandt Cycle for Oxygen Separation. [PDF]
Urduza DC +4 more
europepmc +1 more source

