Results 111 to 120 of about 512,433 (365)

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

Hemodynamic variables in piglets anesthetized with isoflurane or propofol, kept under spontaneous ventilation and FIO2 of 0.5 [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
This study aimed to evaluate comparatively the effects of propofol or isoflurane on hemodynamic variables in piglets that received inspired oxygen fraction (FIO2) of 0.5 under spontaneous ventilation.
C.K. Ido, P.E.S. Silva, H.R.A. Silva, E.G.F. Biteli, R.L. Carneiro, P.C.F. Lopes, A.P. Gering, N. Nunes   +7 more
doaj   +2 more sources

Characteristics of patients making serious inhaler errors with a dry powder inhaler and association with asthma-related events in a primary care setting [PDF]

, 2016
Acknowledgements The iHARP database was funded by unrestricted grants from Mundipharma International Ltd and Research in Real-Life Ltd; these analyses were funded by an unrestricted grant from Teva Pharmaceuticals.
Bosnic-Anticevich, Sinthia, Burden, Anne, Carter, Victoria, Chrystyn, Henry, Gruffydd-Jones, Kevin, Haughney, John, Henrichsen, Svein Høegh, Hutton, Catherine, Infantino, Antonio, Lavorini, Federico, Lisspers, Karin, Papi, Alberto, Price, David B., Roche, Nicolas, Roman-Rodriguez, Miguel, Ryan, Dermot, Ställberg, Björn, Thompson, Samantha L., van der Molen, Thys, Westerik, Janine A. M.   +19 more
core   +6 more sources

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Prenatal cigarette smoke exposure sensitizes acetaminophen-induced liver injury by modulating miR-34a-5p in male offspring mice

Frontiers in Cell and Developmental Biology
Introduction: Cigarette smoke (CS) exacerbates the severity of diseases not only in lungs, but also in systemic organs having no direct contact with smoke.
Daram Yang, Hyuneui Jeong, Min-Seok Kim, Sang-Ik Oh, Kyuhong Lee, Jong-Won Kim, Jong-Won Kim, Bumseok Kim   +7 more
doaj   +1 more source

A new sighting study for the fixed concentration procedure to allow for gender differences [PDF]

, 2011
The fixed concentration procedure (FCP) has been proposed as an alternative to the median lethal concentration (LC50) test (organisation for economic co-operation and development (OECD) test guideline [TG] 403) for the assessment of acute inhalation ...
Charlotte Price, David Griffiths, Greiner M., Ian Indans, Nigel Stallard, Oecd., Oecd., Oecd., Philippa Edwards, Price C., Robert Guest, Stuart Creton   +11 more
core   +2 more sources

Pyrophosphate‐Containing Calcium Phosphates Negatively Impact Heterotopic Bone Quality

Advanced Healthcare Materials, EarlyView.
The role of calcium pyrophosphate (Ca‐PP) in heterotopic bone formation and material degradation is investigated using calcium phosphate (CaP) compositions with varying Ca‐PP content. Results show that Ca‐PP does not impede heterotopic bone formation, minimally affects CaP degradation at non‐osseous sites, and increases phagocytosis.
Martina Jolic, Isabella Åberg, Omar Omar, Håkan Engqvist, Thomas Engstrand, Anders Palmquist, Peter Thomsen, Furqan A. Shah   +7 more
wiley   +1 more source

Comparison of dermal and inhalation routes of entry for organic chemicals [PDF]

The quantitative comparison of the chemical concentration inside the body as the result of a dermal exposure versus an inhalation exposure is useful for assessing human health risks and deciding on an appropriate protective posture.
Clewell, Harvey J., III, Jepson, Gary W., Mcdougal, James N.   +2 more
core   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ, Hollmann, Markus W, Konkel, Moritz, Oei, Gezina TML, Patel, Hemal H, Preckel, Benedikt, Smit, Kirsten F, Weber, Nina C   +7 more
core   +1 more source

Controlled Magnesium Ion Delivery via Mg‐Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a controllable degradation system for Mg‐based biomaterials using sputtering technology, marking a significant advancement in nerve regeneration research. The Mg‐sputtered nerve conduits demonstrate enhanced biocompatibility, biofunctionality, mechanical compatibility, and precise magnesium release, resulting in improved axonal ...
Hyewon Kim, Jieun Kwon, Hyeok Kim, Sunhee Lee, Seongchan Kim, Ji‐Young Lee, Khandoker Asiqur Rahaman, Taeyeon Kim, Hyojin Lee, Myoung‐Ryul Ok, Seok Chung, Hyung‐Seop Han, Yu‐Chan Kim   +12 more
wiley   +1 more source