All opinions are not equal: Toward a consensual approach to the development of drug policy
Abstract Drug policy has been subjected to much scrutiny from different stakeholder groups who present sometimes very different opinions on solutions to address a problem. Reconciling such differences, that are underpinned by both anecdotal and empirical evidence, is a priority yet to be fully achieved.
Gabriel T. W. Wong, Matthew Manning
wiley +1 more source
DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells
This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang+4 more
wiley +1 more source
Abstract Background Sinus surgery removes inflamed tissue, restores airflow, and improves delivery of medication into surgically opened spaces. The exhalation delivery system with fluticasone (EDS‐FLU; XHANCE®) uses a novel delivery system to create closed‐palate, positive‐pressure, bidirectional mechanics that significantly alter the deposition of the
Randall A. Ow+6 more
wiley +1 more source
The experimental modification of germ cells. II. The effect upon the domestic fowl of the daily inhalation of ethyl alcohol and certain related substances [PDF]
Raymond Pearl
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In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao+19 more
wiley +1 more source
AN ACCOUNT OF CASES OF CONSUMPTION TREATED BY IODINE INHALATION, WITH THE IODINE FORMULA. [PDF]
Charles H. Scudamore
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ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease
ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen+10 more
wiley +1 more source
MANUALLY ASSISTED AND CONTROLLED RESPIRATION: ITS USE DURING INHALATION ANESTHESIA FOR THE MAINTENANCE OF A NEAR-NORMAL PHYSIOLOGIC STATE-A REVIEW [PDF]
W. G. Watrous+2 more
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Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury
This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao+5 more
wiley +1 more source