Results 171 to 180 of about 526,857 (343)
Advanced Science, EarlyView.This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang +9 more
wiley +1 more source
Operation for Scirrhus of the Left Breast Performed during the Inhalation of Sulphuric Aether [PDF]
W.P. Brookes
openalex +1 more source
Advanced Science, EarlyView.Compared to transplantation of neural stem cells (NSCs) alone, the combined treatment of NSCs with semaglutide more effectively improves motor dysfunction in Parkinson's disease (PD) mice. This synergistic effect may result from semaglutide's ability to suppress microglial activation, thereby preventing the transformation of resting astrocytes into ...
Dan Song +6 more
wiley +1 more source
Some Account of the First Use of Sulphuric Ether by Inhalation in Surgical Practice [PDF]
George Hayward
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Localized pulmonary edema in cats after the inhalation of a war gas (CH3)2SO4 [PDF]
, 1918 J. Auër
openalex +1 more source
Advanced Science, EarlyView.Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser +11 more
wiley +1 more source
The Development of Inhalation Anæsthesia in the Second Half of the Nineteenth Century [PDF]
, 1946 B. M. Duncum
openalex +1 more source
Advanced Science, EarlyView.This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing +18 more
wiley +1 more source
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source