When did we start calling it silicosis? A historical perspective on the naming of an occupational disease. [PDF]
Zanatta A +3 more
europepmc +1 more source
Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li +23 more
wiley +1 more source
Inhaled Halogen-Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis. [PDF]
Juncos JXM +9 more
europepmc +1 more source
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye +18 more
wiley +1 more source
Functional <sup>17</sup>O-MRI of cerebral oxygen consumption in the activated rat brain. [PDF]
Tourais A +5 more
europepmc +1 more source
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang +14 more
wiley +1 more source
Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang +7 more
wiley +1 more source
Assessment of the autonomic response to a high dose CO<sub>2</sub> inhalation challenge based on heart rate variability and skin conductance in a healthy population. [PDF]
Laar HD +3 more
europepmc +1 more source
Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley +1 more source

