Results 51 to 60 of about 742,635 (391)

Pharmacokinetic study of thymol after intravenous injection and high-dose inhalation in mouse model. [PDF]

, 2019
Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has been
Luo, Mary Z, Tashkin, Donald P, Xie, Kevin, Zhang, Jack Y   +3 more
core   +2 more sources

Diagnosis and management of inhalation injury: an updated review

Critical Care, 2015
In this article we review recent advances made in the pathophysiology, diagnosis, and treatment of inhalation injury. Historically, the diagnosis of inhalation injury has relied on nonspecific clinical exam findings and bronchoscopic evidence.
Patrick F. Walker, M. Buehner, Leslie Wood, N. Boyer, I. Driscoll, J. Lundy, L. Cancio, K. Chung   +7 more
semanticscholar   +1 more source

The economic burden of asthma and chronic obstructive pulmonary disease and the impact of poor inhalation technique with commonly prescribed dry powder inhalers in three European countries

BMC Health Services Research, 2016
BackgroundAsthma and chronic obstructive pulmonary disease (COPD) are common chronic inflammatory respiratory diseases, which impose a substantial burden on healthcare systems and society.
A. Lewis, S. Torvinen, P. Dekhuijzen, H. Chrystyn, A. Watson, M. Blackney, A. Plich   +6 more
semanticscholar   +1 more source

Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats [PDF]

, 2006
Pregnant Sprague–Dawley rats were exposed to ethylbenzene (EB; 0, 250, or 1000 ppm) and methylethylketone (MEK; 0, 1000, or 3000 ppm), alone and in combination, by inhalation, for 6 h/day, during days 6–20 of gestation.
Bourges-Abella, Nathalie, Cadot, R., Gallissot, Frédéric, Lambert, A.M., Morel, G., Sabaté, Jean-Philippe, Saillenfait, Anne-Marie   +6 more
core   +1 more source

Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]

, 2016
The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A, Chung, KF, Dai, R, Gong, J, Gow, A, Guo, C, Hodgson, A, Hussain, F, Leo, B, Martin, NG, Porter, A, Ryan, M, Seiffert, J, Smith, R, Tetley, T, Warren, J, Zhang, J, Zhu, J   +17 more
core   +1 more source

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease [PDF]

, 2013
The aim of the study was to characterize pharmacokinetics of tiotropium solution 5 µg compared to powder 18 µg and assess dose-dependency of tiotropium solution pharmacodynamics in comparison to placebo.
Cornelissen, PJG, Derom, Eric, Disse, B, Hohlfeld, JM, Peterkin, V, Sharma, A, Towse, L, van Noord, JA   +7 more
core   +1 more source

INHALATION EXPOSURE TO CARBON NANOTUBES (CNT) AND CARBON NANOFIBERS (CNF): METHODOLOGY AND DOSIMETRY

Journal of Toxicology and Environmental Health. Part B, Critical Reviews, 2015
Dedicated to Professor Paul Morrow, 1922–2013 In respectful and fond memory of a devoted scientist, inspirational colleague, caring mentor, selfless friend, and in gratitude for his lasting groundbreaking contributions to inhalation toxicology Carbon ...
G. Oberdörster, V. Castranova, B. Asgharian, Phil Sayre   +3 more
semanticscholar   +1 more source

Influence of excipients on spray-dried powders for inhalation [PDF]

, 2014
Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi, Azarmi, Begat, Chan, Chew, Chew, Conti, Corrigan, Coucke, Derom, Edwards, Ely, En-Yu Xu, Farid, Glover, Gray, Griesenbach, Hao-Ying Li, Hooton, Jalalipour, Jing Guo, Kamiya, Kobayashi, Learoyd, Learoyd, Li, Li, Li, Li, Li, Mishra, Momeni, Parsons, Patton, Peter C. Seville, Prakash Rao, Seville, Seville, Sham, Sinn, Sou, Sou, Ståhl, Vergote, Ying Xu, Zeng   +45 more
core   +1 more source

Studies on hepatotoxicity induced by chlorinated hydrocarbons. II. Lipid metabolism and absorption spectrum of microsomal lipid in the mice exposed to 1, 1, 2, 2-tetrachloroethane [PDF]

, 1970
Female Cb mice weighing 20-23 g were exposed to 800 ppm (in average) of 1, I, 2, 2.tetrachloroethane for 3 hours. Both triglyceride and phospholipid in the liver and plasma were determined at varying times after the exposure.
Tomokuni, Katsumaro
core   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source