Results 101 to 110 of about 1,979,534 (305)
Advanced Science, EarlyView.Cancer vaccines face limitations in pancreatic cancer due to insufficient tumor antigens. This ionic liquid ILvax via local tumor delivery triggers robust cDC1‐dependent systemic anti‐tumor immunity. It boosts endogenous CD8+ T cells and optimizes adoptive TCR‐T function, providing a promising synergistic therapeutic strategy.
Junming Huang +11 more
wiley +1 more source
ToxicsMechanically fibrillated cellulose nanofibers, known as fib-CNF (fiber length: 500 nm; diameter: 45 nm), are used in composites and as a natural thickener in foods. To evaluate their safety, we conducted a 28-day study in mice with inhalation exposure at
Yoshihiro Yamashita +7 more
doaj +1 more source
Pharmaceutics, 2019 The objective of the present work was to characterize the ability of liposomes and cyclodextrin (CyD) complexes to modulate the in vivo profile of fluticasone (FTZ). In vitro cell compatibility tests were performed, exposing A549 cells to FTZ in the free
Marina G. Dogbe +5 more
doaj +1 more source
Inhalation therapy in children [PDF]
, 2014 Inhalation is a form of treatment used in respiratory diseases that allows medications to be administered directly to the affected site. Thanks to this, the administration of lower doses helps obtain a higher concentration in the target organ and ...
Jolanta Pietrzak +5 more
core +1 more source
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source
Jurnal Urologi Indonesia, 2019 Objective: To prove and analyze the difference of sperm motility, viability, and concentration of Sprague Dawley rats which were exposed to nicotine inhalation, with rats treated with N-acetyl cysteine (NAC) orally and exposed to nicotine inhalation ...
Dwi Waskito +2 more
doaj +1 more source
Advanced Science, EarlyView.Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim +9 more
wiley +1 more source
In vitro atomization analysis and evaluation of inhalable sodium sivelestat formulations.
PLoS ONEThe purpose of this paper was to study in vitro atomization properties of the self-developed sodium sivelestat for inhalation, evaluate the feasibility of this preparation as an aerosol inhalation, and provide the guidance for the following animal ...
Rangdong Liu +4 more
doaj +1 more source
Iranian Journal of Allergy, Asthma and Immunology, 2018 Kaempferol, a phytochemical found in many edible plants, is known to alleviate diseases such as cancer, allergy, and inflammation. The objective of this study was to investigate whether kaempferol could reduce omega-6 and ovalbumin-mediated allergic ...
Da Rae Kang +4 more
doaj +1 more source
Ethanol Enhanced in Vivo Gene Delivery with Non-Ionic Polymeric Micelles Inhalation
, 2008 Modifications of both carriers and host barriers have been investigated for efficient inhalation gene delivery to lung. Here we used a biocompatible, non-ionic poly(ethyleneoxide) -poly(propyleneoxide)-poly( ethyleneoxide) (PEO-PPO-PEO) polymeric ...
Chao, Yen-Chin; Chang, Shwu-Fen; Lu, Shao-Chun; Hwang, Tzyh-Chang; Hsieh, Wei-Hsien; Liaw, Jiahorng +1 more
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