Results 11 to 20 of about 221,058 (283)

Pharmacokinetic study of thymol after intravenous injection and high‐dose inhalation in mouse model [PDF]

Pharmacology Research & Perspectives, 2019
Thymol is generally recognized as a safe substance by the FDA and has been widely used in the pharmaceutical, food, and cosmetic industries. Pharmacokinetic (PK) studies of thymol have been previously conducted for oral administration, but there has been
Kevin Xie, Donald P. Tashkin, Mary Z. Luo, Jack Y. Zhang   +3 more
doaj   +3 more sources

Inhaled turmerones can be incorporated in the organs via pathways different from oral administration and can affect weight-gain of mice

Scientific Reports, 2022
Turmerones (α-turmerone, β-turmerone, and ar-turmerone) are the major volatile compounds in turmeric (Curcuma longa), a perennial herb of the ginger family.
Yuki Takemoto, Chihiro Kishi, Hinano Ehira, Nobutaka Matsui, Taichi Yamaguchi, Yuri Yoshioka, Shinichi Matsumura, Tatsuya Moriyama, Nobuhiro Zaima   +8 more
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To Enhance Mucus Penetration and Lung Absorption of Drug by Inhalable Nanocrystals-In-Microparticles

Pharmaceutics, 2022
To effectively achieve the pulmonary delivery for curcumin (CN), novel inhalable mucus-penetrating nanocrystal-based microparticles (INMP) were designed. The D-Tocopherol acid polyethylene glycol 1000 succinate (TPGS) modified CN nanocrystals (CN-NS@TPGS)
Guiting Huang, Shuyuan Shuai, Weicheng Zhou, Yingchong Chen, Baode Shen, Pengfei Yue   +5 more
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Nanocrystals based pulmonary inhalation delivery system: advance and challenge

Drug Delivery, 2022
Pulmonary inhalation administration is an ideal approach to locally treat lung disease and to achieve systemic administration for other diseases. However, the complex nature of the structural characteristics of the lungs often results in the difficulty ...
Pengfei Yue, Weicheng Zhou, Guiting Huang, Fangfang Lei, Yingchong Chen, Zhilin Ma, Liru Chen, Ming Yang   +7 more
doaj   +1 more source

Multifunctional nanocarriers for lung drug delivery [PDF]

, 2020
Nanocarriers have been increasingly proposed for lung drug delivery applications. The strategy of combining the intrinsic and more general advantages of the nanostructures with specificities that improve the therapeutic outcomes of particular clinical ...
Grenha, Ana, Pontes, Jorge Filipe
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Aerosol Inhalation of Heat-Killed Clostridium butyricum CGMCC0313-1 Alleviates Allergic Airway Inflammation in Mice

Journal of Immunology Research, 2022
Epidemiological studies have shown that exposure to beneficial microorganisms can reduce the risk of asthma, but the clinical use of live probiotics is controversial due to the risk of infection.
Laodong Li, Qixiang Sun, Huan Xiao, Qiannan Zhang, Siyue Xu, Lejin Lai, Zhengning Li, Chaoqian Li   +7 more
doaj   +1 more source

PLA Microparticles for Pulmonary Delivery of AntiTB drugs: Biodistribution study [PDF]

, 2008
A dry powder inhalable (DPI) microparticles comprising anti-tuberculosis drugs incorporated in biodegradable polymers was developed for the treatment of pulmonary tuberculosis (P. Muttil _et al_. 2007).
Amit Misra, Awadh Bihari Yadav, Jatinder Kaur, Kauslender Kumar, Rahul Kumar Verma   +4 more
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Duration of Hospitalization in Association with Type of Inhalation Therapy Used in the Management of Children with Nonsevere, Acute Bronchiolitis

Pediatrics and Neonatology, 2016
Acute bronchiolitis is one of the main respiratory emergencies in young children. Although supportive therapy is recommended, substantial inconsistency in the clinical usage of inhaled treatments has been reported.
Jamie M. Pinto, Janet L. Schairer, Anna Petrova   +2 more
doaj   +1 more source

Electroencephalogram of Healthy Horses During Inhaled Anesthesia. [PDF]

, 2015
BackgroundPrevious study of the diagnostic validity of electroencephalography (EEG) to detect abnormalities in equine cerebral cortical function relied on the administration of various drugs for sedation, induction, and maintenance of general anesthesia ...
Aleman, MR, Brosnan, RJ, Fletcher, DJ, Holliday, TA, Kass, PH, LeCouteur, RA, Steffey, EP, Tharp, B, Williams, DC   +8 more
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Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure [PDF]

, 2017
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood.
Hurley, Joyce Harts, Johnson, Philip Lee, Kunkler, Phillip Edward, Oxford, Gerry Stephen, Zhang, LuJuan   +4 more
core   +1 more source