Results 261 to 270 of about 631,677 (337)

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Association between the Apolipoprotein E4 and Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Intravenous Anesthesia and Inhalation Anesthesia

open access: yesAnesthesiology, 2012
Ying-min Cai   +8 more
semanticscholar   +1 more source

PDCD5 Contributes to Airway Epithelial Cell Damage via Mitochondrial Pathway and Participates in COPD Pathogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Airway epithelial injury plays a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Mitochondrial dysfunction is implicated in this injury, while the underlying mechanism remains incompletely understood. RNA sequencing was conducted to identify key genes involved in mitochondrial dysfunction in airway epithelial
Hu Shan   +9 more
wiley   +1 more source

Clinical Application of Rapid Inhalation Induction of Anesthesia Using Isoflurane and Sevoflurane with Nitrous Oxide in Dogs.

open access: bronze, 1995
Tatsushi Mutoh   +6 more
openalex   +2 more sources

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Vocal Fold Scar Treatment via Controlled Dexamethasone Delivery With a Light‐Activatable Implant

open access: yesThe Laryngoscope, EarlyView.
A light‐activatable dexamethasone implant was employed for the treatment of vocal fold (VF) scarring in a rabbit model. The implant enables controlled, repeatable drug release via near‐infrared laser irradiation, improving biomechanics, vibratory function, and histological architecture at the injury site.
Denzel Ryan D. Cruz   +6 more
wiley   +1 more source

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