Results 281 to 290 of about 631,677 (337)
Pediatric Discovery, EarlyView.Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li +7 more
wiley +1 more source
Advantages and Technique of Carbon Dioxid Filtration with Inhalation Anesthesia
R. Waters
semanticscholar +1 more source
Deciphering the Heterogeneity of Pulmonary Macrophages in Response to Fine Particles
Small, EarlyView.This study introduces a dual‐labeled gold nanoparticle model to capture particle–responsive cells via integrating fluorescence‐activated cell sorting and single‐cell RNA sequencing. Fourteen macrophage subsets are identified with response and function heterogeneity, among which AMs_3, AMs_7, and recMacs_4 subsets show stronger phagocytic activation ...
Qing'e Shan +11 more
wiley +1 more source
Small, EarlyView.This work develops a theranostic wound microneedle dressing integrates a therapeutic MXene‐infused hydrogel with a high‐conductive sensor array enabled by a novel laser‐scribing technique. The platform actively promotes wound healing and provides antibacterial action while continuously monitoring seven key biomarkers.
Md Sharifuzzaman +6 more
wiley +1 more source
Small, EarlyView.Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad +11 more
wiley +1 more source
Small Science, EarlyView.Herein, a liver‐targeted nanohybrid formulation, SGLC/DOX@AG, is developed to enhance doxorubicin delivery and reduce vascular toxicity in hepatocellular carcinoma (HCC) treatment. Incorporating an albumin–glucosamine lipid complex, the system shows potent anticancer effects and minimized side effects across in vitro, in vivo, and cancer‐on‐a‐chip ...
Hyelim Kim +11 more
wiley +1 more source
Veterinary Record, EarlyView.Abstract Background The recovery period is associated with the greatest risk of injury for horses undergoing anaesthesia. Recovery quality and duration can be influenced by the volatile agent. Methods This prospective, randomised blinded clinical investigation recruited 101 healthy client‐owned horses undergoing elective surgery at one UK equine ...
Kate White, John Hird, Polly Taylor
wiley +1 more source
A new strategy of construction of porcine myocardial infarction model for preclinical research
VIEW, EarlyView.This study proposes a strategy based on the anatomical classification of the porcine left coronary artery (LCA) to establish a stable and reproducible myocardial infarction (MI) model for preclinical research. A combination of LCA classification into nine types via angiography, screening of candidate subtypes, and application of a novel embolic ...
Shixing Huang +10 more
wiley +1 more source
Recent advances of non‐invasive sensors for smart wearable respiratory monitoring
VIEW, EarlyView.Respiration contains rich physiological and pathological information, making it one of the most fundamental and continuous vital signs. Respiration monitoring is a non‐invasive and simple, but incredibly powerful, tool for assessing health, managing disease, and tracking fitness.
Jianhui Chen +8 more
wiley +1 more source