Results 61 to 70 of about 631,677 (337)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Non-invasive control of oxygen consumption during inhalation anesthesia of antireflux laparoscopic interventions by the method of Minimal flow

Patologìâ, 2020
Aim: to study the features of the general anesthesia of antireflux laparoscopic interventions in abdominal surgery using sevoflurane by the method of Low flow, Minimal flow from the standpoint of the ERAS protocol. Materials and methods. The study was
V. I. Chernii, I. V. Shtompel
doaj   +1 more source

Total intravenous anesthesia produces outcomes superior to those with combined intravenous–inhalation anesthesia for laparoscopic gynecological surgery at high altitude

Journal of International Medical Research, 2017
Objective We compared efficacy and adverse outcomes following totally intravenous anesthesia (TIVA) versus combined intravenous–inhalation anesthesia (CIVIA) on hemodynamics and postoperative recovery following laparoscopic gynecological (LG) surgery at ...
Rui Xu, Shuqin Zhou, J. Yang, Haiyan Li, Qing-guo Zhang, Guohong Zhang, Shiyuan Xu, Qing Peng   +7 more
semanticscholar   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

Effects of propofol-based total intravenous anesthesia versus inhalation anesthesia on long-term survival in patients undergoing cancer surgery: a systematic review and meta-analysis [PDF]

, 2022
Yaxing Tang, Lele Tang, Yuting Yao, He Huang, Bing Chen   +4 more
openalex   +1 more source

Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats [PDF]

, 2016
BACKGROUND: Although emergence from general anesthesia is clinically treated as a passive process driven by the pharmacokinetics of drug clearance, agents that hasten recovery from general anesthesia may be useful for treating delayed emergence ...
Ba, Demba E, Brown, Emery N., Chemali, Jessica J., Cotten, Joseph F., Kenny, Jonathan D., Kim, Seong-Eun, Solt, Ken, Taylor, Norman E., Van Dort, Christa J.   +8 more
core   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Depth of Anesthesia Determination by using Bispectral Index in Patients underwent Inhalation or Total Intravenous General Anesthesia

مجله دانشکده پزشکی اصفهان, 2008
BACKGROUND: Bispectral index (BIS) is a new method for determination depth of anesthesia. In most of our operating rooms depth of anesthesia is measured according to clinical features; however, it has not enough accuracy.
Gholam Reza Kalili, Parvin Sajedi, Forough Afsharyzadeh   +2 more
doaj  

COMPARATIVE ASSESSMENT OF CONCOMITANT INHALATIONAL ANESTHESIA MODES IN THE SURGICAL TREATMENT OF MORBID OBESITY

Вестник анестезиологии и реаниматологии, 2017
A randomized trial was conducted in 22 patients with a body mass index of 44.9 ± 1.6 kg/m2 and morbid obesity who underwent endoscopic sleeve gastroplasty.
M. I. Neimark, R. V. Kiselev, A. A. Pantyushin   +2 more
doaj   +1 more source

Inhalation anesthesia and stress in children with oncological pathology

Zdorovʹe Rebenka, 2022
Background. Children with cancer undergo many ­operations and procedures that require anesthesia in the acute phase of the disease or during remission. An integral element of a safe anesthesia plan is the consideration of direct tumor effects.
V.I. Snisar, D.V. Myronov
doaj   +1 more source