Results 121 to 130 of about 44,337 (260)

Preventive Application of House Dust Mite‐Sublingual Immunotherapy Induces Blocking Antibodies in Sensitized Preschool Children

Allergy, EarlyView.
HDM‐pSLIT induced IgG, IgG1, and IgG4 specific to major HDM allergens in sensitized non‐allergic preschool children without increasing HDM‐sIgE. It blunted the development of new sensitizations and reduced HDM reactivity in skin and basophils. HDM‐pSLIT treated children displayed a blocking effect on HDM‐induced basophil activation.
Varsha Dwivedi, Klara Schmidthaler, Hilal Demir, Justyna Sieber, René Gaupmann, Livia Mia Gona‐Höpler, Christina Bannert, Saskia Gruber, Eleonora Dehlink, Thomas Eiwegger, Alexandra Graf, Barbara Bohle, Zsolt Szépfalusi   +12 more
wiley   +1 more source

Inhaled ciclesonide for outpatients with COVID-19: A meta-analysis

Journal of Microbiology, Immunology and Infection, 2022
Chi-Kuei Hsu, Chien-Ming Chao, Chih-Cheng Lai   +2 more
doaj   +1 more source

Evaluation of surrogate inflammatory markers for optimizing inhaled corticosteroid therapy in a real-life clinical setting

, 2003
BackgroundTo determine the effects of 1 months treatment with optimized high-dose inhaled corticosteroid on surrogate markers of airways inflammation, as well as lung function, in a clinical setting.MethodsNine steroid-treated asthmatics (mean dose 778μg/
Fowler, Stephen J, Lipworth, Brian J., Syme-Grant, Nicola J, Syme-Grant, Nicola J., Carey, Frank A, Lipworth, Brian J, Fowler, Stephen J.; id_orcid, Carey, Frank A.   +7 more
core   +1 more source

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma

Allergy, EarlyView.
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler, Sally E. Wenzel, Steve D. Groshong, Mario Castro, Ian D. Pavord, Klaus F. Rabe, Elizabeth Laws, Alexandre Jagerschmidt, Kaitlyn Gayvert, Sivan Harel, Jennifer D. Hamilton, Nikhil Amin, Lu Zhang, Heming Xing, Anissa Elfakir, Bema Coulibaly, Souâd Naimi, Sara Hamon, Paul J. Rowe, Frank Nestle, Danen M. Cunoosamy, Emanuele de Rinaldis, Leda P. Mannent   +22 more
wiley   +1 more source

An integrative review of systematic reviews related to the management of breathlessness in respiratory illnesses

, 2010
Background: breathlessness is a debilitating and distressing symptom in a wide variety of diseases and still a difficult symptom to manage. An integrative review of systematic reviews of non-pharmacological and pharmacological interventions for ...
Chris D Bailey, Rasha Dabbour, Dabbour Rasha, Bailey Chris D, Ann Caress, Bailey, Chris D., Richard Wagland, Smith, Jaclyn, Smith, Jaclyn; id_orcid, Alex Molassiotis, Wagland, Richard, Bailey, Chris, Caress Ann, Molassiotis, Alex, Wagland Richard, Caress, Ann, Molassiotis Alex, Dabbour, Rasha, Smith Jaclyn, Jaclyn Smith   +19 more
core   +1 more source

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta‐analysis of three independent birth cohorts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine retinal nerve fibre layer (RNFL) characteristics in relation to prenatal and postnatal smoking exposure in three independent birth cohorts: two Danish and one Australian cohort. Methods A combined meta‐analysis of peripapillary retinal nerve fibre thickness in the Copenhagen Prospective Studies on Asthma in Childhood 2000 ...
Linna Zhu, Inger Christine Munch, Samantha Sze‐Yee Lee, David A. Mackey, Tamo Sultan, Klaus Bønnelykke, Bo Chawes, Michael Larsen, Nicklas Brustad   +8 more
wiley   +1 more source

Prevalence of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease Patients With Frequent Exacerbations

Allergy, EarlyView.
Mireille C. Melles, Johannes C. C. M. in 't Veen, Dirk‐Jan Slebos, Frits M. E. Franssen, Marlies van Dijk, Pieter‐Paul W. Hekking   +5 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Incidence and Early‐Life Risk Factors for Food Allergy in a Spanish Birth Cohort

Acta Paediatrica, EarlyView.
ABSTRACT Aim The prevalence of food allergy has increased in recent decades. We aimed to determine the cumulative incidence of food allergy in early childhood and to identify associated risk factors. Methods We conducted a prospective birth cohort study including 1006 newborns recruited over one year at a single hospital in Spain and followed until 4 ...
Jorge García‐Ezquiaga, Patricia Torija‐Berzal, Sergio Quevedo‐Teruel, Teresa Bracamonte‐Bermejo, Patricia Alonso‐López, Luis Echeverría‐Zudaire, María Luz García‐García   +6 more
wiley   +1 more source