Results 191 to 200 of about 68,339 (362)

In-vitro and particle image velocimetry studies of dry powder inhalers [PDF]

, 2020
Larissa Gomes dos Reis, Vishal Chaugule, David F. Fletcher, Paul M. Young, Daniela Traini, Julio Soria   +5 more
openalex   +1 more source

Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression

Advanced Science, EarlyView.
This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng, Shuang Cai, Chen Guo, Shaker Khan, Lefan Liu, Qiong Tian, Zhiyuan Ma, Jian Zhang, Lingyu Zhao   +8 more
wiley   +1 more source

Opinion and Knowledge of Pulmonologists, Primary Care Physicians, and Nurses About Inhaled Therapy in COPD. Inhal-Epoc Survey. [PDF]

Int J Chron Obstruct Pulmon Dis
De Miguel-Díez J, Giner Donaire J, Gómez Sáenz JT, Trigueros Carrero JA, Artigas Feliu R, Cruz Culebra N, Plaza V.   +6 more
europepmc   +1 more source

<p>Randomized dose-finding study of batefenterol via dry powder inhaler in patients with COPD</p>

, 2019
Courtney Crim, Michael L. Watkins, Eric Bateman, Gregory Feldman, Isabelle Schenkenberger, Edward Kerwin, C. Gerald Crawford, Krishna Pudi, Shuyen Ho, Charlotte A. Baidoo, Ramiro Castro‐Santamaria   +10 more
openalex   +2 more sources

Health-care Resource Requirements and Potential Financial Consequences of an Environmentally Driven Switch in Respiratory Inhaler Use in England

, 2021
Darsuh Attar-Zadeh, Harriet Lewis, Martina Orlović   +2 more
openalex   +1 more source

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

Advanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao, Xiaofan Jiang, Md Moniruzzaman, Alexandra Mueller, Taskeen Iqbal Janjua, Nisha Tyagi, Zhi Qu, Kuan Yau Wong, Yuran Feng, Aayushi Ghodasara, Ekaterina Strounina, Benjamin P. Ross, Tushar Kumeria, Sumaira Z. Hasnain, Amirali Popat   +14 more
wiley   +1 more source

Neighborhood socioeconomic disadvantage and school stock inhaler utilization in a statewide program. [PDF]

Front Public Health
Reyes SM, Knitter A, Wan W, Gerald LB, Hardy PL, Pappalardo AA, Salem E, Weigley S, Volerman A.   +8 more
europepmc   +1 more source

Inhalation Therapy [PDF]

Journal of the Royal Society of Medicine, 1980
openaire   +2 more sources

Optical diagnostics studies of air flow and powder fluidisation in Nexthaler®. Part II: Use of fluorescent imaging to characterise transient release of fines from a dry powder inhaler

, 2018
C. Merusi, G. Brambilla, E. J. Long, G. K. Hargrave, H. K. Versteeg   +4 more
openalex   +2 more sources

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source