Results 191 to 200 of about 67,891 (311)

The effectiveness of single inhaler triple therapy in patients with bronchial asthma in real clinical practice

open access: diamond, 2022
В. В. Наумова   +3 more
openalex   +2 more sources

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao   +18 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

A guide for a patient-centric approach to asthma management: results of a European Delphi consensus programme. [PDF]

open access: yesNPJ Prim Care Respir Med
Braido F   +7 more
europepmc   +1 more source

NIR‐Triggered Upconversion‐Perovskite Heterostructures for Non‐Genetic, Implant‐Free Optoelectronic Neuromodulation

open access: yesAdvanced Science, EarlyView.
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang   +19 more
wiley   +1 more source

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