Results 271 to 280 of about 68,339 (362)

A Prospective Study of Inhaled Therapy Prescribing, Pressurised Metered-Dose Inhaler (pMDI) Technique Assessment, and Inhaler Concordance Monitoring Among Hospitalised Adult Patients With Airways Disease. [PDF]

Cureus
Lai L, Cockerill B, Lunn E, Abdelgardir R, Teoh YX, Antunes G.   +5 more
europepmc   +1 more source

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Efficacy and safety of different inhaler types for asthma and chronic obstructive pulmonary disease. a systematic review and meta-analysis. [PDF]

NPJ Prim Care Respir Med
Loftus MJ, Cumpston MS, Barnes S, Blakey J, Glanville A, McDonald S, Pattuwage L, Rees M, Silk R, White H, Turner T, Leder K.   +11 more
europepmc   +1 more source

Molecular characterization of the A52 murine hepatocellular carcinoma cell line

Animal Models and Experimental Medicine, EarlyView.
Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman, Eun Jin Sun, Miriam Wankell, Matt A. Field, Ulf Schmitz, Lionel Hebbard   +5 more
wiley   +1 more source

Barriers and Facilitators to Inhaler Adherence in Elderly Individuals with Chronic Obstructive Pulmonary Disease: A Qualitative Study. [PDF]

Int J Chron Obstruct Pulmon Dis
Liu YR, Zhang W, Huang Y, Peng X, Sun K, Wu Z, Wang H, Ji X, Wang J.   +8 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Air pollution, inhaled therapy and COPD exacerbations in Yunlin, Taiwan: a 2016-2024 single-centre retrospective cohort with environmental and carbon-footprint analyses. [PDF]

BMJ Open Respir Res
Chen CY, Huang LY, Cheng BW.
europepmc   +1 more source

An ultra‐processed food‐based cafeteria diet induces obesity, metabolic dysfunction, and tissue‐specific gene dysregulation in C57BL/6 mice

Animal Models and Experimental Medicine, EarlyView.
This schematic figure illustrates the experimental design and key findings of the study. Forty male C57BL/6 mice were assigned to either a standard diet control group or a cafeteria diet (CAFD) group for 16 weeks. CAFD induces obesity, insulin resistance (HOMA‐IR), hepatic steatosis, and dysregulation of a number of genes in visceral and subcutaneous ...
Guilherme Coutinho Kullmann Duarte, Daisy Crispim, Shiva Cerutti Wittée, Joana Raquel Nunes Lemos, Natalia Emerim Lemos, Mayara Souza de Oliveira, Melissa Daniele Alves, Eloísa Toscan Massignam, Tais Silveira Assmann, Felipe Mateus Pellenz   +9 more
wiley   +1 more source

NEXThaler<i>^®</i> in Focus: Evaluating Inhalers' Expectations, Experiences, and Preferences Across Patients, General Practitioners, and Specialists. [PDF]

J Clin Med
Damiański P, Wojakiewicz M, Dębowski T, Piotrowski WJ, Białas AJ.   +4 more
europepmc   +1 more source

The correlation between the level of therapy adherence and inhalation technique in children with uncontrolled asthma using a smart inhaler: the IMAGINE study

Esther Sportel, Boony Thio, Kris L. L. Movig, Job van der Palen, Marjolein Brusse   +4 more
openalex   +1 more source