Results 111 to 120 of about 8,423,921 (236)
Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz +19 morewiley +1 more sourceT1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods
Thirty individuals with MS (mean age: 47.5 ± Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen +10 morewiley +1 more sourceInteraction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective
Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez +75 morewiley +1 more sourceNeurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods
Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik +5 morewiley +1 more sourceInherent optical properties and diffuse attenuation coefficient aggregated within +/-6 nm of SeaWiFS, MODIS-AQUA, VIIRS, OLCI and MERIS bands, corrected Version 2019-06-12
, 2019 Inherent optical properties and diffuse attenuation coefficient aggregated within +/-6 nm of SeaWiFS, MODIS-AQUA, VIIRS, OLCI and MERIS bands, corrected Version 2019-06 ...David Antoine (7457561), Mati Kahru (3191728), Ondrusek, Michael, Astrid Bracher (6959816), Schroeder, Thomas, Poulton, Alex J, Klein, Holger, Muller-Karger, Frank E, Moisan, Tiffany, Jean-François Berthon (7457573), P Jeremy Werdell (7457651), Mitchell, Brian G, Werdell, P Jeremy, Vittorio E Brando (7457582), Lesley Clementson (6980849), Timothy J Smyth (7457642), Barker, Kathryn, Malcolm Taberner (7457558), Ledesma, Santiago, Brian Greg Mitchell (7457624), Kenneth Voss (6375611), Brotas, Vanda, Grant, Michael, Sathyendranath, Shubha, William M Balch (6978683), Michael Ondrusek (7457636), Taberner, Malcolm, Heidi Sosik (7457648), Tiffany Moisan (7457627), Alex J Poulton (6966590), Frouin, Robert, Loisel, Hubert, Richard Crout (5331485), García-Soto, Carlos, Kahru, Mati, Valente, André, McKee, David, Clementson, Lesley, Hervé Claustre (6979724), Milton Kampel (3995831), Robert Arnone (7457564), Borsheim, Knut Yngve, Voss, Kenneth, André Valente (7457549), Shubha Sathyendranath (6973457), Repecaud, Michel, Michael Grant (78621), Stanford B Hooker (7457603), Vanda Brotas (7457552), Berthon, Jean-François, Platt, Trevor, Smyth, Timothy J, Arnone, Robert, Chavez, Francisco P, Knut Yngve Borsheim (7457579), Gibb, S W, S W Gibb (7457597), Frank E Muller-Karger (7457630), Robert Frouin (7457594), Matrai, Patricia A, Brando, Vittorio E, Andres Cianca (7457591), Patricia A Matrai (7457618), Susanne Kratzer (7457606), Kudela, R M, Raymond G Barlow (7457567), Denise Smythe-Wright (7457645), Kampel, Milton, Holger Klein (3577619), Richard Gould (7457600), R M Kudela (7457609), Cianca, Andres, Smythe-Wright, Denise, Michel Repecaud (7457639), Hubert Loisel (7457615), Besiktepe, Sukru, Hooker, Stanford B, Simon Wright (7457657), Santiago Ledesma (7457612), Groom, Steve, David McKee (7457621), Antoine, David, Canuti, Elisabetta, Zibordi, Giuseppe, O'Dowd, Leonie, Sukru Besiktepe (7457576), Kratzer, Susanne, Steve Groom (7457555), Wernand, Marcel Robert, Francisco P Chavez (7457588), Carlos García-Soto (6918173), Thomas Schroeder (303739), Giuseppe Zibordi (4745883), Sosik, Heidi, Marcel R Wernand (7457654), Twardowski, Michael S, Crout, Richard, Bracher, Astrid, Trevor Platt (6973421), Vellucci, Vincenzo, Wright, Simon, Barlow, Raymond G, Vincenzo Vellucci (6010559), Elisabetta Canuti (7457585), Balch, William M, Bélanger, Simon, Simon Bélanger (7457570), Claustre, Hervé, Kathryn Barker (5542361), Michael S Twardowski (7106252), Gould, Richard, Leonie O'Dowd (7457633) +111 morecore +1 more sourceQuantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.Valentina Camera, Agnese Tamanti, Silvia Messina, Nicola Dall'Osto, Teresa Maltempo, Stefano Ziccardi, Matteo Foschi, Maria Grazia Piscaglia, Diana Ferraro, Francesco Crescenzo, Francesca Rossi, Albulena Bajrami, Sabrina Marangoni, Damiano Marastoni, Francesca Benedetta Pizzini, Maria Isabel Leite, Roberta Magliozzi, Patrick Waters, Massimiliano Calabrese, Jacqueline Palace, Ruth Geraldes +20 morewiley +1 more sourceNatural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives
Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa +3 morewiley +1 more source