Results 111 to 120 of about 1,685,014 (305)

Enhancing Covid-19 Decision-Making by Creating an Assurance Case for Simulation Models

open access: yes, 2020
Simulation models have been informing the COVID-19 policy-making process. These models, therefore, have significant influence on risk of societal harms.
Alexander, Rob   +6 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Mammographic density and risk of breast cancer by tumor characteristics: a case-control study

open access: yesBMC Cancer, 2017
Background In a previous paper, we had assumed that the risk of screen-detected breast cancer mostly reflects inherent risk, and the risk of whether a breast cancer is interval versus screen-detected mostly reflects risk of masking.
Kavitha Krishnan   +7 more
doaj   +1 more source

Ambiguity Aversion and Incompleteness of Financial Markets [PDF]

open access: yes
It is widely thought that incomes risks can be shared by trading infinancial assets. But financial assets typically carry some riskidiosyncratic to them, hence, disposing incomes risk using financial assetswill involve buying into the inherent ...
Jean-Marc Tallon, Sujoy Mukerji
core  

Rebuilding the Infrastructure for At-risk Youth [PDF]

open access: yes, 2009
The term "at-risk youth" generally refers to those ages 10 to 17, vulnerable to delinquency, violence, substance abuse, or involvement with the justice system.
Barry Krisberg, Linh Vuong
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Managing Crop Production Risk with Crop Index Insurance Products [PDF]

open access: yes
Index crop insurance products can eliminate the asymmetric information problem inherent in farm-level multiple peril crop insurance. Purchasers of index insurance products are, however, exposed to basis risk.
Barnett, Barry J.   +3 more
core   +1 more source

Stochastic Optimal Power Flow Based on Data-Driven Distributionally Robust Optimization

open access: yes, 2018
We propose a data-driven method to solve a stochastic optimal power flow (OPF) problem based on limited information about forecast error distributions. The objective is to determine power schedules for controllable devices in a power network to balance ...
camacho   +8 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Incidence of Risk Factors on Establishing the Rental Payment by the Lessors [PDF]

open access: yesAnnals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics, 2011
In this paper, we shall expose the risks inherent to leasing operations, undertaken by the lessor, and their influence on establishing the debtor installment afferent to these operations.
Maria Andrada GEORGESCU
doaj  

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