Results 21 to 30 of about 240,405 (258)
Optimization of reactivity temperature feedback and core design of GFR
BackgroundGas-cooled fast reactor (GFR) is one of the six recommended nuclear reactor types of Generation IV Forum (GIF) with the lowest technical maturity.
ZHOU Mengfei, YI Xuan, LIU Guoming
doaj +1 more source
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Optimizing the Design of Small Fast Spectrum Battery-Type Nuclear Reactors
This study is focused on defining and optimizing the design parameters of inherently safe “battery” type sodium-cooled metallic-fueled nuclear reactor cores that operate on a single stationary fuel loading at full power for 30 years.
Staffan Qvist
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Safety Assessment Curve (SAC) for Inherent Safety Assessment in Petrochemical Industry
This paper highlights the development of a new numerical approach for safety assessment called Safety Assessment Curve (SAC). Most of the current methods for assessing inherent safety are index based method.
S.I. Ahmad +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Inherent Safety Assessment Technique for Preliminary Design Stage
Safety is defined as accidents prevention through appropriate technologies to identify and eliminate hazards before an accident occurs. Safety program that prevents hazards in the first place is preferable compared to the typical approaches of ...
S.I. Ahmad, H. Hashim, M.H. Hassim
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The concept of the inherent safety characteristic on thermal-hydraulic of the pool-type sodium-cooled fast reactor was proposed and its formation mechanism was analyzed.
ZHOU Zhiwei;XUE Xiuli;YANG Yong;YANG Hongyi
doaj

