Results 201 to 210 of about 869,931 (335)

Exclusive Se‐O Coordination and Fe‐doping Complementation: A Catalytic Strategy for Enhanced Sulfur Redox in Li‐S Batteries

open access: yesAdvanced Science, EarlyView.
Exclusive Se‐O coordination and Fe‐doping complementation significantly improve conductivity and modulate the d‐band centers, which strongly anchor polysulfides in bidirectional catalysis and reduce the energy barriers for the Li2S nucleation and dissociation, achieving high‐apacity retention, exceptional rate capability, and stable cycling capability.
Zhao Yang   +6 more
wiley   +1 more source

Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β‐Thalassemia

open access: yesAdvanced Science, EarlyView.
Context of Research: β‐thalassemia affects millions worldwide. DNMT inhibitors are effective HbF‐inducers that benefit patients with β‐thalassemia. Existing DNMT inhibitors are not approved for β‐thalassemia treatment due to dose‐limiting toxicity.What We Find: DMT207 traps DNMT1 into helix‐kinked inactive conformation and enhances its interaction with
Yijie Shen   +19 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

open access: yesAdvanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang   +8 more
wiley   +1 more source

Deciphering Spastic Ataxia: Clinical and Genetic Profiles. [PDF]

open access: yesNeurol Genet
Damásio J   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy