Results 31 to 40 of about 3,060 (258)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

EXPLICAŢII TERMINOLOGICE ALE CONCEPTULUI DREPTULUI LA MOŞTENIRE

open access: yesStudia Universitatis Moldaviae: Stiinte Sociale, 2009
The research of a law institution implies a detailed interpretation of the legal instruments specific for this field. The legal terms as inheritance, heir, deceased, inheritance part, succession represents basic pillars of right to inheritance.
USM ADMIN
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The Certificate of Inheritance – Legal Nature and Probative Value

open access: yesBulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law, 2022
The certificate of inheritance is the final act of the notary succession procedure which serves as proof of quality of heir and the property right of the accepted heirs over the goods of the successor mass, in the amount awarded to each heir. Doctrine
Diana G. Ionas
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Reform of Latvian Inheritance Law

open access: yesLaw: Journal of the University of Latvia
In 2009, Latvia started modernizing the Inheritance Law part of the Civil Law adopted in 1937, and on 1 July 2014 the first amendments to this part entered into force. On 1 January 2025, the latest amendments to the Inheritance Law part of the Civil Law
Kristīne Zīle, Annija Kārkliņa
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Conceptual and Ideological Changes in the Czechoslovak Inheritance Law After 1948 in the Broader Context of Changes in Property and Family Law

open access: yesKrakowskie Studia z Historii Państwa i Prawa
This article focuses on the development of Czechoslovak inheritance law in the period after the end of the World War II, with an emphasis on the years from 1945 to 1951.
Jindřich Psutka, Denisa Kotroušová
doaj   +1 more source

Іnheritance of money and right on deposit in a financial institution

open access: yesПроблеми Законності, 2016
Features of inheritance of money and the right on deposit in a financial institution, on the one hand, related to those functions that they perform as the objects of inheritance law in civil circulation, on the other hand, with their specific legal ...
А. М. Ісаєв
doaj   +1 more source

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