Results 181 to 190 of about 361,318 (294)

An Improved NSGA‐III With Hybrid Crossover Operator for Multi‐Objective Optimization of Complex Combined Cooling, Heating, and Power Systems

Energy Science &Engineering, EarlyView.
ABSTRACT Traditional combined cooling, heating, and power (CCHP) systems are highly efficient in energy utilization but face challenges such as high operational costs, CO2 emissions, and complex scheduling. In traditional CCHP systems, typically used in large commercial settings like hospitals or shopping centers, daily operational costs can exceed ...
Lejie Ma, Dexuan Zou
wiley   +1 more source

Familial restrictive cardiomyopathy with novel missense variant of uncertain significance in the FLNC gene

ESC Heart Failure, EarlyView.
Ryo Nakayama, Toshikazu D. Tanaka, Shunsuke Inoue, Jun Yoshida, Jun Hasegawa, Tomohisa Nagoshi, Seitaro Nomura, Hiroyuki Morita, Michihiro Yoshimura   +8 more
wiley   +1 more source

Optimal Design of a Micro Reversible Pump Turbine for Balancing Generation Mode and Storage Mode

Energy Science &Engineering, EarlyView.
In this article, a genetic optimization algorithm for impeller control using Bessel curves is proposed to optimize the micro‐pumped storage unit by integrating the adaptation method of suction chamber/pressure chamber and volute. The superiority and accuracy of the optimization results are confirmed through comparison with numerical simulation results ...
Tengjiao Guo, Jiale Pan, Ran Tao, Ruofu Xiao   +3 more
wiley   +1 more source

Identification of regulatory variants of carboxylesterase 1 (CES1): A proof‐of‐concept study for the application of the Allele‐Specific Protein Expression (ASPE) assay in identifying cis‐acting regulatory genetic polymorphisms

PROTEOMICS, Volume 23, Issue 1, January 2023., 2023
Abstract It is challenging to study regulatory genetic variants as gene expression is affected by both genetic polymorphisms and non‐genetic regulators. The mRNA allele‐specific expression (ASE) assay has been increasingly used for the study of cis‐acting regulatory variants because cis‐acting variants affect gene expression in an allele‐specific ...
Lucy Her, Jian Shi, Xinwen Wang, Bing He, Logan S. Smith, Hui Jiang, Hao‐Jie Zhu   +6 more
wiley   +1 more source

Pharmacogenomics of drug efficacy in the interferon treatment of chronic hepatitis C using classification algorithms

Advances and Applications in Bioinformatics and Chemistry, 2010
Wan-Sheng Ke1, Yuchi Hwang2, Eugene Lin21Department of Internal Medicine, Kuang Tien General Hospital, Taichung County, Taiwan; 2Vita Genomics, Inc., Jung-Shing Road, Wugu Shiang, Taipei, TaiwanAbstract: Chronic hepatitis C (CHC) patients often stop ...
Wan-Sheng Ke, Yuchi Hwang, Eugene Lin
doaj  

Synthetic Biology‐Based Engineering Cells for Drug Delivery

Exploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi, Shuangshuang Hu, Xindi Qian, Wenlu Yan, Yaping Li   +4 more
wiley   +1 more source

Pedigree reconstruction for triploid apple cultivars using single nucleotide polymorphism array data

PLANTS, PEOPLE, PLANET, Volume 5, Issue 1, Page 98-111, January 2023., 2023
Many economically, culturally, and historically important apple cultivars are triploids, which have three copies of each chromosome instead of the more typical two copies in diploids. Despite their prevalence and importance, there have been conflicting reports regarding their origin and their ability to beget diploids.
Nicholas P. Howard, Diego Micheletti, James J. Luby, Charles‐Eric Durel, Caroline Denancé, Hélène Muranty, Matthew Ordidge, Dirk C. Albach   +7 more
wiley   +1 more source

Functional, pathogenic, and pharmacological roles of protein folding intermediates

Proteins: Structure, Function, and Bioinformatics, EarlyView., 2023
Abstract Protein expression and function in eukaryotic cells are tightly harmonized processes modulated by the combination of different layers of regulation, including transcription, processing, stability, and translation of messenger RNA, as well as assembly, maturation, sorting, recycling, and degradation of polypeptides.
Emiliano Biasini, Pietro Faccioli
wiley   +1 more source

SDF‐Guided Point Cloud Generation Framework for Mesh‐Free CFD

International Journal for Numerical Methods in Fluids, EarlyView.
This paper presents different methods for generating clouds of points around objects for use with meshless methods in computational fluid dynamics. This image shows the cloud generated around the original ROBIN body. ABSTRACT Meshing is a bottleneck of CFD workflows, especially when complex geometries are considered.
Tao Zhang, George N. Barakos
wiley   +1 more source

Lightweight and conformal acousto‐ultrasonic sensing network for multi‐scale structural health monitoring: A review

FlexMat, EarlyView.
This systematic review mainly covers a collection of acousto‐ultrasonic sensors, two modalities of network installation, and their employment with multi‐scale monitoring methods. The weight increase and conformability of different sensing networks are discussed, as the two major challenges for developing structural health monitoring systems of complex ...
Yehai Li, Shifeng Guo, Zhongqing Su, Keqin Ding, Xian Jun Loh   +4 more
wiley   +1 more source