Results 11 to 20 of about 69,200 (270)

Genetic heterogeneity in familial forms of genetic generalized epilepsy: from mono- to oligogenism [PDF]

open access: yesHuman Genomics
Genetic generalized epilepsy (GGE) including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy (JME), and GGE with tonic–clonic seizures (TCS) (GGE-TCS), is genetically influenced with a two- to four- fold increased risk ...
Maha Dahawi   +22 more
doaj   +2 more sources

Intraoperative diagnosis of hypertrophic cardiomiopathy [PDF]

open access: yesPediatric Anesthesia and Critical Care Journal (PACCJ), 2021
Hypertrophic cardiomyopathy (HCM) is the most com- mon genetic disease of the heart. Autosomal dominant inheritance leading to mutation in one of the numerous genes encoding for proteins in the myocardial sarcomere leads to abnormal myocyte growth with ...
I. Bekiroglu, R. Heng, J. D. Tobias
doaj   +1 more source

Epigenetic opportunities for evolutionary computation

open access: yesRoyal Society Open Science, 2023
Evolutionary computation is a group of biologically inspired algorithms used to solve complex optimization problems. It can be split into evolutionary algorithms, which take inspiration from genetic inheritance, and swarm intelligence algorithms, that ...
Sizhe Yuen   +2 more
doaj   +1 more source

The concept of genetic programming in organizing internal transport processes [PDF]

open access: yesArchives of Transport, 2015
The paper presents proposition of using genetic algorithm to support organization of internal transport processes in logistics facilities. The organization of internal transport can be done through solving optimization task of scheduling internal ...
Konrad Lewczuk
doaj   +1 more source

Application of New Modified Genetic Algorithm in Inverse Calculation of Strong Source Location

open access: yesAtmosphere, 2022
With the rapid development of intelligent systems, the application of genetic algorithms to quickly and accurately determine the location of hazardous gas leaks is of great practical significance.
Jiming Yao   +5 more
doaj   +1 more source

A proximal LAVA method for genome-wide association and prediction of traits with mixed inheritance patterns

open access: yesBMC Bioinformatics, 2021
Background The genetic basis of phenotypic traits is highly variable and usually divided into mono-, oligo- and polygenic inheritance classes. Relatively few traits are known to be monogenic or oligogeneic. The majority of traits are considered to have a
Patrik Waldmann
doaj   +1 more source

Exome sequencing in 116 patients with inherited thrombocytopenia that remained of unknown origin after systematic phenotype-driven diagnostic workup

open access: yesHaematologica, 2022
Inherited thrombocytopenias (IT) are genetic diseases characterized by low platelet count, sometimes associated with congenital defects or a predisposition to develop additional conditions.
Caterina Marconi   +15 more
doaj   +1 more source

Genomic landscape of a three-generation pedigree segregating affective disorder. [PDF]

open access: yesPLoS ONE, 2009
Bipolar disorder (BPD) is a common psychiatric illness with a complex mode of inheritance. Besides traditional linkage and association studies, which require large sample sizes, analysis of common and rare chromosomal copy number variants (CNVs) in ...
Shuzhang Yang   +6 more
doaj   +1 more source

Polyploidy breaks speciation barriers in Australian burrowing frogs Neobatrachus [PDF]

open access: yes, 2020
Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation.
Booker, William   +11 more
core   +4 more sources

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