Results 201 to 210 of about 361,318 (294)

Long‐term use of low‐dose aspirin for cancer prevention: A 20‐year longitudinal cohort study of 1,506,525 Hong Kong residents

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Low‐dose aspirin use over an extended period is associated with a reduced risk of colorectal cancer (CRC) and potentially other malignancies. Duration of use to derive such benefits, however, remains unclear. This retrospective study examined low‐dose aspirin use for possible chemoprotective effects among individuals in Hong Kong.
Amy Lam   +6 more
wiley   +1 more source

A Learning Model with Memory in the Financial Markets

open access: yesInternational Journal of Finance &Economics, EarlyView.
ABSTRACT Learning is central to a financial agent's aspiration to gain persistent strategic advantage in asset value maximisation. The implicit mechanism that transforms this aspiration into an observed value gain is the speed of error corrections (demonstrating, an agent's speed of learning) whilst facing increased uncertainty.
Shikta Singh   +6 more
wiley   +1 more source

Novel machine‐learning bioinformatics reveal distinct metabolic alterations for enhanced colorectal cancer diagnosis and monitoring

open access: yesiMetaOmics, EarlyView.
The PANDA pipeline for colorectal cancer (CRC) analysis integrates metabolomic data from LC‐MS with machine learning techniques to classify CRC stages and predict biomarkers. Initially, the raw metabolomic data is processed using partial least squares discriminant analysis (PLS‐DA) to reduce dimensionality and highlight key features.
Rui Xu   +8 more
wiley   +1 more source

Ensemble and consensus approaches to prediction of recessive inheritance for missense variants in human disease. [PDF]

open access: yesCell Rep Methods
Petrazzini BO   +6 more
europepmc   +1 more source

A panoramic view of cotton resistance to Verticillium dahliae: From genetic architectures to precision genomic selection

open access: yesiMeta, EarlyView.
This study identified 10 reliable quantitative trait loci (QTLs) governing cotton resistance to V. dahliae in various environments through a genome‐wide association analysis (GWAS) using an upland cotton population. The pyramid of these 10 elite alleles reduced the disease index of cotton to V. dahliae from 70 to 20.
Xiaojun Zhang   +30 more
wiley   +1 more source

Identifying individuals with rare disease variants by inferring shared ancestral haplotypes from SNP array data. [PDF]

open access: yesNAR Genom Bioinform
Robertson E   +9 more
europepmc   +1 more source

Synthetic biology for medical biomaterials

open access: yesInterdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu   +4 more
wiley   +1 more source

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