A statistical model for estimating maternal-zygotic interactions and parent-of-origin effects of QTLs for seed development. [PDF]
PLoS ONE, 2008 Proper development of a seed requires coordinated exchanges of signals among the three components that develop side by side in the seed. One of these is the maternal integument that encloses the other two zygotic components, i.e., the diploid embryo and ...
Yanchun Li +10 more
doaj +1 more source
Organellar inheritance in the green lineage: insights from Ostreococcus tauri [PDF]
, 2013 Along the green lineage (Chlorophyta and Streptophyta), mitochondria and chloroplast are mainly uniparentally transmitted and their evolution is thus clonal. The mode of organellar inheritance in their ancestor is less certain.
Adam Eyre-Walker +56 more
core +1 more source
Inheritance-Based Diversity Measures for Explicit Convergence Control in Evolutionary Algorithms
, 2018 Diversity is an important factor in evolutionary algorithms to prevent premature convergence towards a single local optimum. In order to maintain diversity throughout the process of evolution, various means exist in literature.
Fortin Félix-Antoine +3 more
core +1 more source
Chloroplast microsatellites: measures of genetic diversity and the effect of homoplasy [PDF]
, 2005 Chloroplast microsatellites have been widely used in population genetic studies of conifers in recent years. However, their haplotype configurations suggest that they could have high levels of homoplasy, thus limiting the power of these molecular markers.
Doyle JJ +15 more
core +3 more sources
In the Light of Deep Coalescence: Revisiting Trees Within Networks [PDF]
, 2016 Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and analyzing these networks.
Nakhleh, Luay, Yu, Yun, Zhu, Jiafan
core +1 more source
Computing Individual Risks based on Family History in Genetic Disease in the Presence of Competing Risks [PDF]
, 2017 When considering a genetic disease with variable age at onset (ex: diabetes , familial amyloid neuropathy, cancers, etc.), computing the individual risk of the disease based on family history (FH) is of critical interest both for clinicians and patients.
Bouaziz, O, Lefebvre, Antoine, Nuel, G
core +3 more sources
A major QTL corresponding to the Rk locus for resistance to root-knot nematodes in cowpea (Vigna unguiculata L. Walp.). [PDF]
, 2016 Key messageGenome resolution of a major QTL associated with the Rk locus in cowpea for resistance to root-knot nematodes has significance for plant breeding programs and R gene characterization. Cowpea (Vigna unguiculata L.
Close, Timothy J +7 more
core +1 more source
Ancestral haplotype reconstruction in endogamous populations using identity-by-descent.
PLoS Computational Biology, 2021 In this work we develop a novel algorithm for reconstructing the genomes of ancestral individuals, given genotype or sequence data from contemporary individuals and an extended pedigree of family relationships.
Kelly Finke +10 more
doaj +1 more source
Evolving dynamic multiple-objective optimization problems with objective replacement [PDF]
, 2005 This paper studies the strategies for multi-objective optimization in a dynamic environment. In particular, we focus on problems with objective replacement, where some objectives may be replaced with new objectives during evolution.
Chen, Q, Guan, SU, Mo, W
core
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source