Results 71 to 80 of about 722,236 (315)
Genome Medicine, 2021 Background Clinical interpretation of genetic variants in the context of the patient’s phenotype is becoming the largest component of cost and time expenditure for genome-based diagnosis of rare genetic diseases.
Francisco M. De La Vega +27 more
doaj +1 more source
On Flexible finite polygenic models for multiple-trait evaluation [PDF]
, 2002 Finite polygenic models (FPM) might be an alternative to the infinitesimal model (TIM) for the genetic evaluation of pedigreed multiple-generation populations for multiple quantitative traits.
Bink, M.C.A.M.
core +2 more sources
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
Pharmaceuticals, 2019 Ferritin is a multimeric protein composed of light (L-ferritin) and heavy (H-ferritin) subunits that binds and stores iron inside the cell. A variety of mutations have been reported in the L-ferritin subunit gene (FTL gene) that cause the following five ...
Beatriz Cadenas +10 more
doaj +1 more source
Neural Architecture Search using Progressive Evolution [PDF]
arXiv, 2022 Vanilla neural architecture search using evolutionary algorithms (EA) involves evaluating each architecture by training it from scratch, which is extremely time-consuming. This can be reduced by using a supernet to estimate the fitness of every architecture in the search space due to its weight sharing nature.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Certain frontotemporal lobar degeneration subtypes, including TDP‐A and B, can either occur sporadically or in association with specific genetic mutations. It is uncertain whether syndromic or imaging features previously associated with these patient groups are subtype or genotype specific.
Sean Coulborn +17 more
wiley +1 more source
IEEE AccessWith the development of the national economy, a large number of small and medium-sized enterprises have rapidly expanded in scale, and their internal structures have become increasingly complex. Traditional single project management is no longer suitable
Rui Zhao, Zhenhua Lei, Ziyu Zhao
doaj +1 more source
THE URGENCY OF GENETIC VERIFICATION OF NON-COMPACTION CARDIOMYOPATHY IN CHILDREN: CLINICAL CASES
Вопросы современной педиатрии, 2018 Background. Non-compaction cardiomyopathy is a group of genetically heterogeneous, poorly studied myocardial diseases with a variety of clinical manifestations (from asymptomatic course to progressive systolic dysfunction with symptoms of chronic heart ...
Nataliya A. Sdvigova +7 more
doaj +1 more source
Organic Selection and Social Heredity: The Original Baldwin Effect Revisited [PDF]
, 2019 The so-called “Baldwin Effect” has been studied for years in the fields of Artificial Life, Cognitive Science, and Evolutionary Theory across disciplines.
Le, Nam
core
On the design of an ECOC-compliant genetic algorithm [PDF]
, 2013 Genetic Algorithms (GA) have been previously applied to Error-Correcting Output Codes (ECOC) in state-of-the-art works in order to find a suitable coding matrix.
Baró Solé, Xavier +3 more
core +1 more source